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The European approach to disinfectant qualification

02/20/2017 07:30:11 AM

Tim Sandle has written an overview of the European approach to disinfectant testing for the A3P publication La Vague.Here is the introduction:Contamination control is of great importance to healthcare facilities and to pharmaceutical cleanrooms. ...

Does studying yellow fever offer Zika clues?

02/19/2017 08:00:20 AM

As cases of Zika virus increase there is considerable investigation and research into the virus. One area being looked at for clues is yellow fever virus. A second area involves the use of mouse models.By Dr. Tim SandleZika virus is a member ...

Quick Laboratory Safety Tips

02/18/2017 07:30:17 AM

There is never a better time than now (excuse the cliche) to evaluate your laboratory safety procedures. For larger facilities, this can be a daunting task but necessary nonetheless. Regardless of lab size, the team at M2 Scientifics has put ...

Insight into the functioning of human gut bacteria

02/17/2017 08:00:19 AM

The human large bowel ("gut") is colonised by an extremely dense population of bacteria, collectively termed the microbiota or "gut flora."Recent research indicates that the microbiota is important for human health and nutrition and has been ...

Good Practice Guidelines for Blood Establishments

02/15/2017 07:00:11 AM

EU directive integrates Council of Europe Good Practice Guidelines for blood establishmentsGood Practice Guidelines have been prepared through co-operation between the European Directorate for the Quality of Medicines & HealthCare of the Council ...

Trail vaccine for leprosy

02/14/2017 07:00:14 AM

Leprosy, also known as Hansen’s disease, is caused by the bacterium Mycobacterium leprae. These Gram-positive, rod-shaped bacteria depend greatly on their host for survival - they have lost many important metabolic genes through the process ...

Control of transmission mechanism mediated of calcium pulses

02/13/2017 07:00:03 AM

A new medical article of interest. looking at the effects of calcium ion depletion on the human cell.The abstract reads:Given the importance of calcium for good functioning of the body and knowing its involvement in signaling mechanisms and ...

Antimicrobial resistant bacteria detected in air pollution

02/12/2017 07:00:15 AM

Areas subject to air pollution contain a growing concentration of bacteria that are resistant to antimicrobials, according to a new study. Consequently, air movement may provide a new ways for their transmission.By Tim SandleThe study, highlighting ...

Model to predict how microbiomes may respond to change

02/11/2017 08:00:12 AM

Scientists studying microbiomes have created a framework for predicting how the composition of these complex microbial communities may respond to changing conditions.The review study, led by Jennifer Martiny, professor of ecology & evolutionary ...

Unique microbial photosynthesis discovered

02/10/2017 07:00:23 AM

Researchers at Washington State University have discovered a new type of cooperative photosynthesis that could be used in engineering microbial communities for waste treatment and bioenergy production.Prosthecochloris aestaurii, a green-tinged, ...

New surgical mask renders viruses harmless

02/09/2017 07:30:16 AM

Hyo-Jick Choi, a professor in the University of Alberta Department of Chemical and Materials Engineering, noticed that many people wear a simple surgical-style mask for protection during outbreaks of influenza or other potentially deadly viruses ...

Medical Device Risk – ISO 14971 Gets It Right

02/08/2017 07:00:14 AM

William Storage has written an interesting article on risk assessment. Here’s a quote from the thought provoking article: “Obvious as those may seem, defining risk in terms of hazards is surprisingly uncommon; leaving severity out of its ...

Effects of storage time and environmental exposure on soil bugs

02/07/2017 07:30:11 AM

Are soil organisms still risky after a year in the sun? International researchers placed trays of soil in and around sea containers, as well as in cupboards, to count the creatures in them every few months. They showcase some of the risks presented ...

Disinfectants: Properties, Applications and Effectiveness

02/06/2017 08:00:12 AM

A new book of interest has been published,m titled "Disinfectants: Properties, Applications and Effectiveness." The book is edited by Ana Sofia Cardoso, Cristina Maria Martins Almeida, Telma Costa Cordeiro, and Vanessa de Jesus Gaffney. The ...

Innovative Strategies for Reducing Nasal Colonization

02/05/2017 08:00:17 AM

Staphylococcus aureus(S. aureus) and methicillin resistant S. aureus (MRSA) can cause difficult-to-treat infections due to their antibiotic resistance. Approximately 90,000 people are affected yearly, and 20,000 people die from infections caused ...

Captive monkeys gain human microbiomes

02/04/2017 08:00:20 AM

To explore how a microbiome adapts to a new environment, University of Minnesota researcher Dan Knights and his colleagues turned their attention to nonhuman primates. According to Bioscience Techniques, the team examined the microbiota from ...

Scientists tissue-engineer functional part of human stomach

02/03/2017 07:30:26 AM

Scientists have used pluripotent stem cells to generate human stomach tissues in a Petri dish that produce acid and digestive enzymes. They grew tissues from the stomach's corpus/fundus region. The study comes two years after the same team generated ...

Key proteins that may make Zika so deadly

02/02/2017 07:00:32 AM

Zika virus has infected hundreds of thousands of people around the world, mostly in the Americas. In the United States and its territories, more than 38,000 Zika cases have been reported so far, most of them in Puerto Rico. There are no vaccines ...

Mathematical modeling to explain antimicrobial resistance

02/01/2017 08:00:08 AM

Modern medicine and treatments for bacterial infections and cancer have significantly increased life spans and improved quality-of-life. However, many drugs eventually fail because of the outgrowth and survival of treatment-resistant populations. ...

Some bacteria express an antibiotic-deactivating factor

01/31/2017 07:00:05 AM

Bacteria that are susceptible to antibiotics can survive when enough resistant cells around them are expressing an antibiotic-deactivating factor. This new take on how the microbial context can compromise antibiotic therapy was published by ...

Secret code language of bacteria revealed

01/30/2017 07:30:22 AM

Antibiotic resistance in pathogenic bacteria is a growing global challenge. Danish researchers have now discovered that bacteria use a code language to avoid being controlled. Understanding this code language will be paramount to developing ...

How to Implement Big Data for Pharmaceutical Supply Chain Management

01/29/2017 14:33:21 PM

Big data and predictive analytics are quickly changing the way most industries do business. By collecting all industry-related data, even the little pieces of data that might seem insignificant, companies can predict trends, find patterns and ...

Estimating time since death using necrobiome

01/29/2017 07:30:24 AM

A team led by Dr. Nathan H. Lents of the John Jay College of Criminal Justice, City University of New York (CUNY), sampled bacteria from the ear and nasal canals of 21 cadavers through several weeks of decomposition. They then analyzed the bacterial ...

How Bacteria Survive Antibiotic Treatment

01/28/2017 08:00:11 AM

Scientists around the world are working hard to win the battle against multi-resistant bacteria. A new publication from the BASP Centre, University of Copenhagen now presents how even sensitive bacteria often manage to survive antibiotic treatment ...

Gene transfer on the fungal highway

01/27/2017 07:30:33 AM

Soil bacteria use the extensively branched, thread-like structures of fungi to move around and access new food sources. In a new study, researchers have been able to demonstrate that these so-called fungal hyphae also form a hot spot for gene ...

European Pharmacopoeia 9th Edition

01/26/2017 08:00:04 AM

A new edition of the European Pharmacopeia is effective from 1st Jan 2017. The following changes have been made: Test for heavy metals have been deleted from the monographs concerned.‘Anhydrous’ has been deleted from the title of the monographs ...

Seoul viral outbreak linked to home-based rat-breeding facilities

01/25/2017 12:18:15 PM

Eight people, who shared the common factor of working at different rat-breeding facilities in two different U.S. states and who contracted Seoul virus, most likely contracted the virus from the rats.Special report by Tim Sandle:This is the outcome ...

Ph. Eur. Commission aimed to reduce animal testing

01/25/2017 08:00:20 AM

The recent adoption at its 156th session of the following texts demonstrates the Commission’s commitment to the replacement, reduction and refinement of animal tests in the quality control of medicines.Ph. Eur. General Chapter Adopted: Su ...

Assuring Data Integrity for Life Sciences (book)

01/24/2017 07:00:02 AM

A useful book has been published - 'Assuring Data Integrity for Life Sciences' - edited by Siegfried Schmitt.This new book provides a truly global perspective on data integrity and the solutions available to address this serious issue. It includes ...

Development of cleanrooms: historical review

01/23/2017 07:00:20 AM

Tim Sandle has traced the history ofcleanrooms in two part feature. Part 1 covers the early concept of clean spaces, as required for surgery, and traces these to developments immediately post-war. Part 2 will address the coming of modern cleanroom ...

Microbiology: An oral history

01/22/2017 07:30:02 AM

A BBC radio program about the history of microbiology is available for download as an mp3:Melvyn Bragg and guests discuss the history of microbiology. We have more microbes in our bodies than we have human cells. We fear them as the cause of ...

Scientists examine bacterium found 1,000 feet underground

01/21/2017 07:30:10 AM

Researchers find a bacterium 1,000 feet underground (called Paenibacillus) that is resistant to 18 different antibiotics and uses identical methods of defense as similar species found in soils. The scientists identified five novel pathways that ...

Contamination Control Under Foot

01/20/2017 08:00:05 AM

Control of airborne and surface microorganisms and airborne particles in a cleanroom is achieved through the physical operation of the heating, ventilation, and air conditioning system and cleaning and disinfection techniques.Even with these ...

Antimicrobial Resistance in the Environment

11/22/2016 07:00:01 AM

The class of chemicals characterized as biocides are used in all parts of society from home to hospital, to farms and industry. The presence of biocides selects for genes in microorganisms that can protect against their lethal effects. These ...

The Science Of Christmas

11/21/2016 16:49:16 PM

This book looks at many of the traditions of Christmas and takes an amusing, sideways look st the science behind Christmas. Just how fast will Santa need to travel to deliver gifts to all the children? Where did tinsel come from and is it safe? ...

Mold Monitoring and Control in Pharmaceutical Manufacturing Areas

11/21/2016 07:00:22 AM

Tony Cundell has written an important article on fungi for American Pharmaceutical Review.The introduction reads:“Recent high profile product recalls associated with mold contamination has resulted in more attention from the FDA to fungal ...

Rapid test for Salmonella in chicken developed

11/20/2016 07:30:34 AM

Microbiologists and technologists have joined forces to come up with a rapid and easy-to-use method to detect Salmonella in food such a chicken. The device contributes to contamination control.Despite multiple warning about food storage and ...

Spatiotemporal microbial evolution on antibiotic landscapes

11/19/2016 07:30:06 AM

An interesting research paper, considering a new way to examine the development of antibiotic resistance:A key aspect of bacterial survival is the ability to evolve while migrating across spatially varying environmental challenges. Laboratory ...

New insight into fungal strategy for infecting plants

11/18/2016 07:30:13 AM

Researchers from UPM id reveal how mould from humidity caused by rotting fruits and vegetables unfolds a surprising strategy to infect plants.A team of researchers from Centre for Plant Biotechnology and Genomics (CBGP, UPM-INIA), has published ...

First-generation Cephalosporins show Promise in Tuberculosis Therapy

11/17/2016 07:30:06 AM

Tuberculosis (TB) is the most deadly infectious disease in the world with treatment spanning for up to 6 months; however, in case of MDR-TB, it can even go up to 2 years. Research shows that the cost of developing a new drug is quite huge. Now, ...

New test for detecting prions in urine

11/16/2016 08:00:34 AM

A new test may detect the presence of abnormal proteins indicative of a deadly prion disease known as Creutzfeldt-Jakob Disease (CJD). By adapting an established blood test for variant CJD, researchers at the University College London say the ...

What role will innovation and regulation play in tackling AMR?

11/15/2016 08:00:03 AM

News from the Royal Society of Biology:A panel of expert speakers and delegates from across the life sciences gathered as part of Biology Week to debate how regulation and innovation can help tackle the antimicrobial resistance crisis.Professor ...

Removal of Endotoxin from Protein in Pharmaceutical Processes

11/14/2016 08:00:09 AM

Bacterial endotoxin is the lipopolysaccharide component of the cell wall of Gram-negative bacteria, together with other cellular material that combines to form an endotoxin complex. Endotoxin is pyrogenic and it presents a risk to patients who ...

New FDA Q7 guidance (APIs)

11/13/2016 08:00:21 AM

The U.S. Food and Drug Administration has issued a new guidance document “Q7 Good Manufacturing Practice Guidance for Active Pharmaceutical Ingredients - Guidance for Industry.”This guidance applies to the manufacture of APIs for use in ...

Rifampicin and antibiotic resistance

11/12/2016 05:00:01 AM

A common antibiotic called rifampicin, used to treat tuberculosis, leprosy, and Legionnaire's disease, is becoming less effective as the bacteria that cause the diseases develop more resistance.One of the mechanisms leading to rifampicin's ...

Insight into Pseudomonas aeruginosa survival mechanism

11/11/2016 08:00:20 AM

The bacterium

UN agrees to take action on antimicrobial resistance

11/10/2016 07:30:04 AM

A statement from the Royal Society for Biology, in relation to the United Nations agreeing to take action on antimicrobial resistance“The Learned Society Partnership on Antimicrobial Resistance (LeSPAR) welcomes news of global political and ...

FDA Bans 19 Antibacterial Ingredients from OTC Products

11/09/2016 07:30:21 AM

The FDA is one of the main institutions to increasingly put efforts in reviewing the efficacy and safety of antibacterial products in the market. The final decision of banning these ingredients came after a series of proposals and enquiries ...

The importance of gut microbiota in C. difficile pathogenesis

11/08/2016 07:30:03 AM

Clostridium difficile infection (CDI) is a major cause of healthcare-associated infections worldwide. CDI can cause symptoms from mild diarrhea to life-threatening toxic megacolon. Antibiotics disrupt the normal intestinal microflora enabling ...

How to write a good science article

11/07/2016 17:17:56 PM

Science can easily be misreported, especially for the wilder headline seeking claims. How can a good science article be structured?

Class of drugs effective against Marburg virus and Ebola

11/06/2016 07:30:05 AM

A new drug has shown promise against both Marburg virus and Ebola. This may not be as surprising as it first seems, given the genetic similarities between the two viruses.Filoviruses cause two types of viral haemorrhagic fever: Marburg and Ebola. ...

Research draws a connection between shingles and stroke

11/05/2016 07:30:03 AM

A new study has drawn a connection between the virus that causes the skin rash shingles with an increased chance of suffering from a stroke in later life.The connection has been made by the American Academy of Neurology. Here researchers, from ...

Antibiotic resistance linked with exposure to chlorhexidine

11/04/2016 16:23:03 PM

Klebsiella pneumoniaebacteria exposed to chlorhexidine-containing disinfectants can become resistant to colistin, a last resort antibiotic often used against multidrug resistant pathogens. This is the first study to link exposure to chlorhexidine ...

Counting microscopic sheep? Human and microbial cell mix revealed

11/04/2016 08:30:03 AM

Pick up a text book on microbiology or human physiology. Chances are you’ll stumble across a reference to the number of microorganisms in the human body exceeding the number of cells ten-fold. But is this correct?The microorganisms together ...

New 'layer' of fungi exposed

11/03/2016 09:00:00 AM

In order to optimally utilise fungi, and to fight them when necessary, we require greater insight into the functions that they can perform. Researchers at TU Delft and Utrecht University have exposed a new layer of functional complexity in fungi. ...

Pharmig news # 65

11/03/2016 06:29:09 AM

A new edition of Pharmig news has been issued (edition 65). In this issue there is an article on the revision to the USP chapter (1231) on pharmaceutical water by Tim Sandle. There is also an article on the microbiological quality of non-sterile ...

VERY, VERY SURPRISING USES FOR BOTOX THAT HAVE NOTHING TO DO WITH FOREHEAD WRINKLES

11/02/2016 18:02:00 PM

When most people think of Botox the first thing that usually comes to mind is wrinkle reduction. Indeed, Botox is the world’s most popular treatment for eradicating wrinkles and fine lines.

Drop in tuberculosis rates in the U.K.

11/02/2016 07:00:02 AM

The annual TB report, published today (September 2016), describes the recent epidemiology of TB in England since the launch of the Collaborative TB Strategy in January 2015. It presents new data to the end of 2015 and provides an update on ...

A new class of antibiotics?

11/01/2016 09:00:23 AM

Researchers have made detailed, atomic-level images of a peroxiredoxin, which has revealed a peculiar characteristic of this protein that might form the foundation for an entirely new class of antibiotics.Peroxiredoxin is needed by all cells ...

Risk Assessment and Management for Healthcare Manufacturing

10/31/2016 08:30:16 AM

Tim Sandle has published a new book titled “Risk Assessment and Management for Healthcare Manufacturing: Practical Tips and Case Studies.”Avoidance of hazards and assessment of risk have long been part of the manufacture of pharmaceuticals ...

Shingles And Asthma Linked Together

10/30/2016 08:00:15 AM

A new study has connected shingles to increased rates of acute cardiovascular events such as ischemic stroke. The same research, from the Mayo Clinic, has drawn a connection between developing shingles and asthma.Shingles (caused by the virus ...

Decline In UK Animal Experiments

10/29/2016 07:30:10 AM

Fewer animals were used in experiments in the U.K. during 2014 compared with 2013 (these are the latest statistics, released in January 2016 by the Home Office). The decline is 6 percent, with some 3.8 million procedures undertaken in 2014.The ...

Tracking the evolution of antibiotic resistance

10/28/2016 07:30:27 AM

Researchers have developed a large culturing device to track the evolution of bacteria as they mutate in the presence of antibiotics, revealing that, surprisingly, the fittest mutants were not those most likely to infiltrate higher antibiotic ...

The microbiome and evolution

10/27/2016 08:00:11 AM

Biotechniques have an interesting articleabout the gut microbiome, the Human Microbiome Project and the role that the microbiome plays in human evolution.Here is an extract:“Scientists have unearthed the fact that drastic differences in m ...

EMA paper on production of water for injections (WFI) by non-distillation methods

10/26/2016 07:30:10 AM

The European Medicines Agency has published a question and answer paper on the production of water for injections (WFI) by non-distillation methods.Water for injections in bulk is obtained from water that complies with the regulations on water ...

UN to tackle the 'fundamental threat' of antibiotic-resistant superbugs

10/25/2016 07:30:28 AM

All 193 UN member states have agreed to combat the proliferation of drug-resistant infections, estimated to kill more than 700,000 people each year, according to The Guardian.The UN secretary general, Ban Ki-moon, said antimicrobial resistance ...

Too much cleanliness is affecting our microbiome for the worse

10/24/2016 08:00:14 AM

Increasing concerns about personal cleanliness, especially with children, could be linked to a reduced the diversity of our microbiomes and increased the prevalence of inflammatory and stress-related diseases. New research gives new weight to ...

Will Big Data Influence Pharmaceuticals for the Better?

10/23/2016 11:19:54 AM

Today, it feels like everything is connected. You can access your files from a computer, a smart phone, a tablet or any other interconnected device — and that only accounts for your own personal files and devices.Guest post by Megan Ray N ...

The Latest Xarelto Lawsuit Update

10/23/2016 11:07:28 AM

In 2011, the Food and Drug Administration (FDA) approved a blood thinner called Xarelto for use in various medical situations. Since Xarelto was approved, manufacturer Janssen Pharmaceuticals has filled over three million orders for the medication. ...

Rapid method for detecting foodborne pathogens

10/23/2016 06:00:02 AM

Researchers have developed a hybrid nanosensor incorporating magnetic resonance and fluorescence. Lab testing of milk showed the detector could sense varying concentrations of a pathogenic strain of E. coli known as O157:H7 in less than an hour. ...

Moist-heat sterilization of blood bags

10/22/2016 08:00:26 AM

Vittorio Mascherpa has written an interesting article on the sterilization of blood collection bags. The abstract reads:“This article provides basic information on the sterilization of blood bags systems by moist-heat. Problems of pressure ...

EMA Determines Certain Drugs Safe from Zika Contamination

10/21/2016 07:30:02 AM

On Sept. 21, 2016, the European Medicines Agency (EMA) announced there is no increased risk of Zika contamination for patients who take plasma- or urine-derived drugs. The conclusion was made after an assessment was carried out by EMA and a ...

WHO guidance on variations to multisource pharmaceutical products

10/20/2016 07:00:28 AM

The World Health Organization has updated Annex 10 of its GMPs “WHO general guidance on variations to multisource pharmaceutical products.”According to the document:“A marketing authorization (MA) holder or applicant is responsible for ...

History of Pharmig

10/19/2016 08:00:17 AM

The history of the Pharmaceutical Microbiology Interest Group (Pharmig)History of Pharmig by Tim Sandle on ScribdPosted by Dr. Tim SandlePharmaceutical Microbiology (c) Dr Tim Sandle http://www.pharmamicroresources.com

A new, epidemic strain of C. difficile is proving deadly

10/18/2016 08:00:20 AM

A new, epidemic strain of C. difficile is proving deadly, and new research from the University of Virginia School of Medicine not only explains why but also suggests a way to stop it.Until now, scientists have not understood what made this strain ...

More flexibility for authorisation of biocidal products

10/18/2016 03:26:13 AM

News on the regulation of biocides in Europe:ECHA/NA/16/31The regulation on the authorisation of same biocidal products has been updated to add new possibilities requested by industry. Companies are now able to get a national authorisation when ...

Control of WFI and Clean Steam Systems for Bacterial Endotoxins

10/17/2016 07:30:18 AM

Bacterial endotoxin presents a risk to several classes of pharmaceutical product, with parenteral products at the greatest risk. Bacterial endotoxin is the lipopolysaccharide (LPS) component of the cell wall of Gram-negative bacteria. It is ...

Introducing Cleanrooms

10/16/2016 07:00:21 AM

This book provides an introduction to cleanrooms and clean air devices in GMP environments. The book explains what cleanrooms are, the contamination risks, key design features, and the requirements for classifying and operating them. The book ...

Design of Cleanrooms – best practice

10/15/2016 07:30:26 AM

While adhering to specific requirements makes designing and constructing a cleanroom more complex than conventional construction projects, the standards serve as a blueprint for the successful completion of a cleanroom that will meet the exacting ...

ATCC® Bacterial Culture Guide

10/14/2016 08:00:33 AM

ATCC offer a Bacterial Culture Guide, which contains general technical information regarding bacterial growth, propagation, preservation, and application. To access the guide, go to ATCC.Posted by Dr. Tim SandlePharmaceutical Microbiology (c) ...

Watch bacteria evolve antibiotic resistance (video)

10/13/2016 07:30:31 AM

Adjusting to ever higher levels of antibiotics preps them to morph into super resistant strains, and scientists can now watch it happen. A new device — a huge petri dish coated with different concentrations of antibiotics — makes this normally ...

Vote for PDA distinguished author or editor

10/13/2016 04:15:49 AM

The voting has opened for the PDA Distinguished Editor or Author award. The Editor/Author with the most votes by Dec. 31 will be awarded the 2016 PDA/DHI Technical Books Distinguished Editor/Author Award at PDA's 2017 Annual Meeting.Five books ...

Detergent selection

10/12/2016 08:00:15 AM

Ensuring that medical equipment is free from soil requires effective cleaning and the selection of an appropriate detergent. For this understanding the chemical characteristics of detergents is necessary in order to make an appropriate choice ...

FDA Amends List of Drugs that May Not Be Compounded

10/11/2016 14:27:51 PM

The Food and Drug Administration (FDA) announced that it is amending regulations to revise the list of drugs that have been withdrawn or removed from the market because the drug products or their components have been found to be unsafe or i ...

Pharmacopeial Forum 42 (5)

10/11/2016 07:00:23 AM

A new edition of the Pharmacopeial Forum Vol. 42, No.5, has been issued. Items of interest include:Chapter197

Making science better: Swap ‘bad science’ with ‘good science’

10/10/2016 07:00:06 AM

In a previous article, we looked at ‘bad science’ including deliberately misleading research. Although not common, bad science still occurs. How can scientific findings be improved? We assess some best practices,In this article: what makes ...

Recoding E. coli to become resistant to all viruses

10/09/2016 18:09:59 PM

Scientists are close to finishing recoding the Escherichia coli bacterium to work with a different genetic code — one that differs to all other genetic codes on Earth, the organism will have some interesting properties.Microbiologists at the ...

Magnetic bacteria carry anti-cancer drugs to tumors

10/08/2016 07:30:11 AM

Studies have taken place in Canada whereby magnetic bacteria are used to power nano-devices, to help ferry anti-cancer medicines to sites of tumors. Such devices offer faster and more precise drug delivery.Researchers in Canada have connected ...

Meet the new virus named influenza D

10/07/2016 07:30:08 AM

A virus, relatively newly detected, that affects cattle has been given a new name: influenza D. The reason for the new naming is because of the virus is distinct from other influenza types — A, B and C.The naming of the virus was decided at ...

Rare trees discovered in the Queen’s garden

10/06/2016 14:28:56 PM

With huge areas of land and many residences Queen Elizabeth II might be forgiven for not knowing the full diversity of flora and fauna. This week botanists report the discovery of rare elms in the royal garden.Elm trees thought to be extinct ...

Stillbirth and bacteria linked for first time

10/06/2016 07:00:25 AM

A common type of bacteria, carried by many women, has been linked with premature delivery and stillbirths. This understanding may help to reduce the number of deaths.Researchers have found that Group B

This Is the Major Problem of Powder Processing

10/05/2016 12:16:09 PM

Powder processing is one of the most common ways to manufacture most medications. Since it can process ingredients in bulk, it is also one of the most efficient ways to make sure the demands for these pharmaceuticals are met in a timely manner. ...

ISO 14644 Part 14 issued

10/05/2016 12:11:50 PM

A new part of the ISO cleanroom series has been issued:ISO 14644-14 links the cleanroom classifications found in the landmark ISO 14644-1:2015, Classification of air cleanliness by particle concentration to the suitability of equipment (e.g., ...

Urinary tract infections in pregnant women

10/05/2016 08:00:12 AM

Urinary tract infections in pregnant women complicate the course of pregnancy. It is necessary to know not only the pathogen type but also to prescribe the safest antibiotics for adequate treatment of urinary tract infections.The prevalence ...

Pharmacopeial Forum 42 (4)

10/04/2016 07:00:28 AM

A new edition of the Pharmacopeial Forum Vol. 42, No.4, has been issued. Items of interest include:Chapter 785 Osmolality and OsmolarityProposed revision details:Add clarity to the text in the Introduction.Add examples of how to convert from ...

What is ‘bad science’ and how to spot it?

10/03/2016 08:00:06 AM

There are many excellent science studies based on well-designed experiments and which make reasoned claims based on the assembled experimental data. While the majority of scientific findings and papers issued each year offer valid findings and ...

Pharmeuropa 28.3

10/02/2016 07:00:01 AM

A new edition of Pharmeuropa has been issued (28.3). Pharmeuropa is an EDQM publication. Draft monographs are published in Pharmeuropa for public enquiry, which lasts for three months. Items of interest are:3.2.3

Inherited Microbiomes?

10/01/2016 07:30:13 AM

Previous work has shown that certain bacterial species are transferred from parents to children. A new study from the Max Planck Institute in Tubingen suggests that part of your microbiome is actually inherited. That is, there are specific genes ...

Preparing for ISO 13485:2016

09/30/2016 08:00:44 AM

The new ISO 13485 revision is here and, for medical device manufacturers, this is significant news. ISO 13485:2016 provides an international standard that can be truly harmonized across multiple regions and regulatory requirements. But it also ...

Draft PIC/S guidance on data integrity

09/29/2016 07:00:33 AM

PIC/S has issued a new draft document relating to data integrity, titled “Good practices for data management and integrity in regulated GMP/GDP environments.” (PI 041-1 (Draft 2)).According to the document:Good data management practices ...