Teixobactin: A Powerful Tool for Combating Resistant Strains

04/22/2017 07:30:06 AM

Resistance to antibiotics has grown out to be serious health dilemma. Despite this serious health crisis, no new antibiotics have been revealed since last 30 y. A new ray of hope in the form of teixobactin has come out of the dark which can ...

Preparation, production, storage and performance testing of culture media

04/21/2017 15:15:19 PM

Spotlight on ISO 11133:2014 “Microbiology of food, animal feed and water -- Preparation, production, storage and performance testing of culture media.”Culture media is of fundamental importance for most microbiological tests: to obtain pure ...

Light rain can spread soil bacteria far and wide

04/20/2017 07:30:31 AM

Using high-resolution imaging, researchers from MIT's Department of Mechanical Engineering observed the effect of raindrops falling on dry soil laden with bacteria. When falling at speeds mimicking those of a light rain, at temperatures similar ...

Faster, more accurate detection of food- and water-borne bacteria

04/19/2017 08:00:25 AM

Recently, Charles S. Henry and colleagues developed a paper-based method to detect Salmonella, Listeria and E. coli in food and water samples. In their latest study, Henry's team wanted to see if it would be feasible to use this paper-based ...

Visualizing the genome: First 3-D structures of active DNA created

04/18/2017 08:00:00 AM

Researchers from the University of Cambridge and the MRC Laboratory of Molecular Biology used a combination of imaging and up to 100,000 measurements of where different parts of the DNA are close to each other to examine the genome in a mouse ...

Understanding the Importance of Safety in Pharmaceutical Manufacturing and Transportation

04/17/2017 12:49:11 PM

Pharmaceutical manufacturing and transportation is an industry that requires a high level of oversight to make sure the medications being manufactured meet the required specifications and that they are being transported correctly to ensure maximum ...

Microbial swab recovery

04/17/2017 07:30:15 AM

Swabs are commonly used as part of microbiological environmental monitoring programmes and it is important to understand the suitability of the swabs used and their limitations.A new paper by Ravikrishna Satyada and Tim Sandle looks into this ...

'Smart' bacteria remodel their genes to infect our intestines

04/16/2017 07:30:20 AM

Infectious diarrhea, a common disease of children, is responsible for over 2 million infant deaths annually in developing counties alone. A primary cause of this and other devastating conditions is enteropathogenic bacteria, which attack the ...

Proposed New USP General Chapter: The Analytical Procedure Lifecycle ?1220?

04/15/2017 07:30:12 AM

The following may be of interest to readers:An analytical procedure must be demonstrated to be fit for its intended purpose. It is useful to consider the entire lifecycle of an analytical procedure, i.e., its design and development, qualification, ...

Humidity Measurement for Effective Manufacturing

04/14/2017 07:30:08 AM

The purpose of this free eBook is to share humidity theory, tools and practical examples of how measuring humidity, moisture and dew point brings value to different manufacturing processes.The eBook includes some of our most popular and requested ...

3-D tissue culture models to mimic human gut infections

04/13/2017 08:00:25 AM

Central to the development of tissue models that can better predict how humans respond to infection is the understanding that cells and tissues in our bodies function in a three-dimensional (3-D) context. Accordingly, cell-based models of tissues ...

Useful links updated

04/12/2017 09:28:29 AM

The list of useful links to science and regulatory organizations on the site has been updated. Please check through, there will be something of interest.A3P (pharmaceutical industry, biotechnological and biomedical response to rapidly changing ...

Phage therapy shown to kill drug-resistant superbug

04/12/2017 08:00:08 AM

Phages are viruses that kill bacteria but are otherwise harmless. A major advantage is that phages only target the harmful bacteria, so there are less side of the effects often associated with antibiotics. Phage therapy however has not had the ...

Beneficial bacteria can offset bowel disease

04/11/2017 08:00:24 AM

In a new report, researchers describe how inflammation can go unchecked in the absence of a certain inhibitor called NLRP12, adding that beneficial bacteria may be the key to helping to reverse a cycle of gut inflammation seen in certain in ...

Biodecontamination of Cleanrooms and Laboratories Using Gassing Systems

04/10/2017 14:26:36 PM

Tim Sandle has written a new article on the decontamination of cleanrooms and laboratories by gassing systems:Cleanrooms, laboratory areas, isolators and biosafety workspaces (microbiological safety cabinets) require a level of cleanliness and ...

New sensor detects inflammatory bowel disease

04/09/2017 07:00:07 AM

Inflammatory bowel disease refers to a set of inflammatory conditions of the colon and small intestine. Examples include Crohn's disease and ulcerative colitis. In the U.S. alone some one million people suffer with one type of the disease.Current ...

3-D tissue culture models to mimic human gut infections

04/08/2017 08:00:35 AM

Central to the development of tissue models that can better predict how humans respond to infection is the understanding that cells and tissues in our bodies function in a three-dimensional (3-D) context. Accordingly, cell-based models of tissues ...

Phage therapy shown to kill drug-resistant superbug

04/07/2017 07:30:01 AM

Phages are viruses that kill bacteria but are otherwise harmless. A major advantage is that phages only target the harmful bacteria, so there are less side of the effects often associated with antibiotics. Phage therapy however has not had the ...

Visualizing the genome: First 3-D structures of active DNA created

04/06/2017 07:30:32 AM

Researchers from the University of Cambridge and the MRC Laboratory of Molecular Biology used a combination of imaging and up to 100,000 measurements of where different parts of the DNA are close to each other to examine the genome in a mouse ...

Beneficial bacteria can offset bowel disease

04/05/2017 08:00:32 AM

In a new report, researchers describe how inflammation can go unchecked in the absence of a certain inhibitor called NLRP12, adding that beneficial bacteria may be the key to helping to reverse a cycle of gut inflammation seen in certain in ...

EDQM Symposium on Microbiology

04/04/2017 08:00:08 AM

The EDQM will hold an international symposium on 10-11 October 2017 in Strasbourg (France) to present and discuss recent achievements, as well as future perspectives, of the Ph. Eur. in the microbiology field.The symposium will cover the recent ...

Risk of microbial spores in cleanrooms

04/03/2017 07:30:11 AM

The risks posed by microbial spores pose to cleanrooms in terms of their survival mechanisms and, in the case of fungi, ease of dispersal, are substantial. One means to address this is through the use of a proven sporidical agent. This is the ...

ISO 31000 revision

04/02/2017 07:30:14 AM

ISO 31000:2009 on risk management is intended for people who create and protect value in an organization by managing risks, making decisions, setting and achieving objectives and improving performance. The standard’s revision process discovers ...

Microbiome diversity is influenced by chance encounters

04/01/2017 07:30:12 AM

Within the human digestive tract, there are trillions of bacteria, and these communities contain hundreds or even thousands of species. The makeup of those populations can vary greatly from one person to another, depending on factors such as ...

Takeaways From The FDA's Revised Quality Metrics Guidance

03/31/2017 07:00:22 AM

On November 23, 2016, the Food and Drug Administration (FDA) published a revised draft guidance for Submission of Quality Metrics Data. The guidance includes significant changes to the earlier quality metrics draft guidance issued by the agency ...

Risk Mitigation When Evaluating Cleanroom Construction Materials

03/30/2017 15:22:13 PM

Maik Jornitz, President, G-Con, has written an interesting white paper on cleanroom construction materials.The introduction reads:Reducing the cost of goods sold has become a focus of pharmaceutical facility, cleanroom, and process design, ...

Why rare microbial species are sometimes important

03/30/2017 07:30:15 AM

Despite the small population of each rare species in a microbial community, such species may number as much as several hundred within a community, such that the so-called "rare biosphere" may account for roughly 20-30 percent of individual bacteria ...

Targeting antimicrobial resistance in the short-term

03/29/2017 07:30:11 AM

While any antimicrobial resistance is concerning, the increasing incidence of antibiotic-resistant Gram-negative bacteria has become a particular problem as strains resistant to multiple antibiotics are becoming common and no new drugs to treat ...

Journal of GXP Compliance Author of the Year award

03/28/2017 07:00:20 AM

Tim Sandle has won the Journal of GXP Compliance Author of the Year award. This was for the following papers submitted to the journal during 2016:“Control of WFI and Clean Steam Systems for Bacterial Endotoxins”“Designing Aseptic Process ...

Top 10 Things to Avoid to Ensure Good Data Integrity Practice

03/27/2017 07:30:16 AM

Bioscience Technology has issued a guide on data integrity, which is free to download.The science site states: “With the advances of technology and the migration of data onto digital platforms, the need for properly and safely sustaining the ...

Antimicrobial substances identified in Komodo dragon blood

03/26/2017 08:00:22 AM

The world's largest lizard, Komodo dragons live on five small islands in Indonesia. The saliva of these creatures contains at least 57 species of bacteria, which are believed to contribute to the demise of their prey. Yet, the Komodo dragon ...

Common bacterium helps control disease-bearing mosquitoes

03/25/2017 09:00:17 AM

Genes from a common bacterium can be harnessed to sterilize male insects, a tool that can potentially control populations of both disease-bearing mosquitoes and agricultural pests, researchers at Yale University and Vanderbilt University re ...

How cells adapt rapidly to zero gravity

03/24/2017 09:00:05 AM

Mammalian cells are optimally adapted to gravity. But what happens in the microgravity environment of space if the earth's pull disappears? Previously, many experiments exhibited cell changes -- after hours or even days in zero gravity. Astronauts, ...

New TB drug candidates developed from soil bacteria

03/23/2017 08:30:27 AM

A new treatment for tuberculosis (TB) is set to be developed using compounds derived from bacteria that live in soil -- according an international collaboration of researchers, including the University of Warwick.The group looked at soil bacteria ...

10 Healthy Eating Tips for the Student

03/22/2017 08:30:22 AM

College students must know how to maintain their body healthily and strong. Their food diet should be well-planned, and they should take their food in time. Eating is compulsory for all of us. But for students, it is more than necessary. They ...

TB Alliance Calls on WHO to Add Tuberculosis to List of Critical Group of Bacteria

03/21/2017 08:30:42 AM

TB Alliance and the broader TB community urge that the World Health Organization (WHO) add Mycobacterium tuberculosis to the critical group within the list of drug-resistant bacteria identified as urgent priorities for research and developm ...

National Poison Prevention Week

03/20/2017 08:30:02 AM

In recognition of National Poison Prevention Week (March 19-25), the National Capital Poison Center urges all parents to take 2 minutes to learn how to prevent and respond to a poison emergency. More than a million poison exposures occur every ...

Which Medicine For Ed Has The Lowest Number Of Side Effects?

03/19/2017 13:04:32 PM

Erectile dysfunction (ED) is pretty common among men with almost half of men between the ages 40 to 70 have some kind of erectile problems.  The Journal of the American Medical Association reported that 7 percent of men aged 18 to 29 and 9 ...

New way to classify viruses based on structure

03/19/2017 09:00:26 AM

Professor Robert Sinclair at the Okinawa Institute of Science and Technology Graduate University (OIST) and Professor Dennis Bamford and Dr. Janne Ravantti from the University of Helsinki have found new evidence to support a classification system ...

Novel genetic switch boosts bacteria cells' production of useful chemicals

03/18/2017 08:30:19 AM

MIT chemical engineers have designed a novel genetic switch that allows them to dramatically boost bacteria's production of useful chemicals by shutting down competing metabolic pathways in the cells.Researchers have been trying to engineer ...

Gut inflammation controlled by changing bacterial balance

03/17/2017 08:00:38 AM

Numerous human diseases, including inflammatory bowel disease, diabetes and autism spectrum disorders have been linked to abnormal gut microbial communities, or microbiomes, but an open question is whether these altered microbiomes are drivers ...

Commonly used pain relievers have added benefit of fighting bacterial infection

03/16/2017 08:30:17 AM

Some commonly used drugs that combat aches and pains, fever, and inflammation are also thought to have the ability to kill bacteria. New research appearing online on March 13 in the Cell Press journal Chemistry & Biology reveals that these drugs, ...

Rainbow dyes add greater precision to fight against 'superbugs'

03/15/2017 08:30:10 AM

The discovery, made possible through a revolutionary method used to color bacterial cell walls developed at IU, is an important step forward in research on bacterial growth and could inform efforts to develop drugs that combat antibiotic-resistant ...

Crosstalk between intestinal microbes and immune system

03/14/2017 08:30:24 AM

The human gut is home to some 100 trillion bacteria, comprising between 250 and 500 species. This astounding array of organisms, collectively known as the gut microbiome, is a powerful regulator of disease and health and has been implicated ...

Sleepy bacteria evolve to resist antibiotics

03/13/2017 09:00:15 AM

Antibiotic resistance is a major and growing problem worldwide. According to the World Health Organization, antibiotic resistance is rising to dangerously high levels in all parts of the world, and new resistance mechanisms are emerging and ...

Is Scott Gottlieb the next FDA Commissioner?

03/13/2017 08:30:46 AM

Scott Gottlieb is President Donald Trump’s choice to lead the agency, according to Bloomberg sources at the White House.Gottlieb, a former deputy commissioner of the FDA under George W. Bush, will look to cut th red tape at the FDA, enabling ...

An Analysis Of FDA FY2016 Drug GMP Warning Letters

03/12/2017 09:00:30 AM

Pharmaceutical on-line has published a useful overview of FDA warning lettersissued in 2016. This comes from Barbara Unger, Unger Consulting Inc.Here are the headline trends:The number of drug GMP warning letters issued more than doubled over ...

Bacteria turn a tick's gut microbes against itself

03/11/2017 08:00:08 AM

Before infecting humans, tick-borne bacteria or viruses first have to get past a tick's defenses to colonize it. How this occurs is not well understood. To investigate, Yale researchers studied a model of the second-most-common tick-borne infection ...

Understanding Airlocks for cGMP Facilities

03/10/2017 08:00:24 AM

The use of airlocks is a principle that is well-established in the design of cGMP facilities. Despite the apparent simplicity of inserting small rooms into the plan of a pharmaceutical manufacturing facility, there is confusion regarding their ...

Recall Report

03/09/2017 15:13:05 PM

A new website of interest called Recall Report:A recall occurs when a medication or product is faulty or has side effects so severe that it becomes potentially dangerous to human health. Recalls happen for a number of reasons, including faulty ...

How to Safely Handle Compressed Gas Cylinders

03/09/2017 08:00:14 AM

The hazards involved in compressed gas use run the gamut from oxygen displacement (inert gas use), fires, explosions, and toxic exposures to the physical hazards of high pressurization. So in this issue, the Safety Guys offer some tips on accident ...

How to gown effectively (video) - part 2

03/08/2017 08:00:24 AM

Here is part 2 of our how to gown properly when entering cleanrooms videos.Practical workshop on good cleanroom gowning from Simon Fiala – Key Account Manager, COMPREI Reinraum. This focuses on technique # 2 (see the first video for an alternative ...

How to gown effectively (video) - part 1

03/07/2017 14:14:07 PM

Effective gowning is an important of contamination control, given that people are the biggest source of contamination in pharmaceutical facilities. To aid good gowning, we're providing two videos showing effective gowning techniques.The first ...

A Closer Look at the Right to Try Act for the Terminally Ill

03/06/2017 07:00:21 AM

There are hundreds of different investigational drugs that are in various phases of clinical trials all over the world. Until they’ve been cleared to be marketed to the public, they are only available in very limited clinical trials. While ...

Vitamin B12 and microbial growth

03/05/2017 07:30:19 AM

Scientists have found more evidence that vitamin B12, a substance produced by only a few organisms but needed by nearly all of them, wields great power in the microbial world. The findings lend credence to the idea that B12 helps shape microbial ...

How to Safely Handle Compressed Gas Cylinders

03/04/2017 08:00:19 AM

The hazards involved in compressed gas use run the gamut from oxygen displacement (inert gas use), fires, explosions, and toxic exposures to the physical hazards of high pressurization. So in this issue, the Safety Guys offer some tips on accident ...

The Science Behind the Detox Fad

03/03/2017 16:28:40 PM

A guest post By Helen Vector.Detox and detoxification have become the latest buzzwords in the diet industry fixated with convincing people (mostly women) that they have found a quick fix that will help them to lose weight fast. We now detox ...

Identifying bacteria using a flow cytometer

03/03/2017 07:30:11 AM

A new, easy-to-adapt and inexpensive analytical procedure has been developed by researchers from the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw. The main role is played by innovative bioconjugates -- luminescent, ...

European and US regulators agree on mutual recognition of inspections

03/02/2017 13:58:32 PM

Important news for those who work in organizations that regularly receive both U.S. FDA and European medicines agency inspectors. This has been a long time coming...a new transatlantic agreement is now in place, designed to will help to make ...

Evidence of the bacterial transfer during space missions

03/02/2017 08:00:35 AM

Most modern organisms require specific conditions to survive: liquid water, oxygen, moderate temperatures, stable aboveground air pressure, and low-level radiation exposure. However, not all terrestrial organisms live harmoniously under such ...

Bacteria inspire synthetic catalysts

03/01/2017 08:00:08 AM

Using a natural catalyst from bacteria for inspiration, researchers have now reported the fastest synthetic catalysts to date for hydrogen production-- producing 45 million hydrogen molecules per second.The chemical bonds in hydrogen gas, for ...

How viruses communicate

02/28/2017 08:00:06 AM

Viruses have been found to communicate with one another, leaving short “posts” for kin and descendants. The messages help the viruses reading them decide how to proceed with the process of infection, according to research.Many viruses face ...

Clean Room Technology in ART Clinics: A Practical Guide

02/27/2017 08:00:08 AM

A new book of interest 'Clean Room Technology in ART Clinics: A Practical Guide', edited by Sandro C. Esteves, Alex C. Varghese, Kathryn C. Worrilow.Regulatory agencies worldwide have issued directives or such requirements for air quality standards ...

Bacteria turn a tick's gut microbes against itself

02/26/2017 08:00:04 AM

Before infecting humans, tick-borne bacteria or viruses first have to get past a tick's defenses to colonize it. How this occurs is not well understood. To investigate, Yale researchers studied a model of the second-most-common tick-borne infection ...

Understanding Airlocks for cGMP Facilities

02/25/2017 08:00:18 AM

The use of airlocks is a principle that is well-established in the design of cGMP facilities. Despite the apparent simplicity of inserting small rooms into the plan of a pharmaceutical manufacturing facility, there is confusion regarding their ...

An Analysis Of FDA FY2016 Drug GMP Warning Letters

02/24/2017 08:00:26 AM

Pharmaceutical on-line has published a useful overview of FDA warning letters issued in 2016. This comes from Barbara Unger, Unger Consulting Inc.Here are the headline trends:The number of drug GMP warning letters issued more than doubled over ...

Advanced Cooling Systems for Blood Product Storage Applications

02/23/2017 07:30:33 AM

Century Refrigeration announces that it designs custom, advanced cooling systems for blood product storage applications, including blood banks and laboratories. The customized nature of the solutions ensures that they are capable of the low ...

Update on Ebola Outbreak and Aftermath in West Africa

02/22/2017 15:39:53 PM

WHAT: Live-streamed panel discussion and Q&A with expert MSF medical and operations staffWHEN: Thursday, February 23, 8 p.m. Eastern Time (recording will be archived online here) WHERE: Register online here DETAILS: The Ebola outbreak that ...

Each animal species hosts a unique microbial community

02/22/2017 07:30:22 AM

Each animal species hosts its own, unique community of microbes that can significantly improve its health and fitness. This is the implication of a laboratory study that investigated four different animal groups and their associated microbiota. ...

Advances in Aseptic Blow-Fill-Seal Processing

02/21/2017 07:30:12 AM

Aseptic blow-fill-seal (B/F/S) systems for the processing of pharmaceutical liquids have experienced rapid and growing acceptance by the pharmaceutical industry over the past 20 years. This has been accelerated by enhancements made to aseptic ...

The European approach to disinfectant qualification

02/20/2017 07:30:11 AM

Tim Sandle has written an overview of the European approach to disinfectant testing for the A3P publication La Vague.Here is the introduction:Contamination control is of great importance to healthcare facilities and to pharmaceutical cleanrooms. ...

Does studying yellow fever offer Zika clues?

02/19/2017 08:00:20 AM

As cases of Zika virus increase there is considerable investigation and research into the virus. One area being looked at for clues is yellow fever virus. A second area involves the use of mouse models.By Dr. Tim SandleZika virus is a member ...

Quick Laboratory Safety Tips

02/18/2017 07:30:17 AM

There is never a better time than now (excuse the cliche) to evaluate your laboratory safety procedures. For larger facilities, this can be a daunting task but necessary nonetheless. Regardless of lab size, the team at M2 Scientifics has put ...

Insight into the functioning of human gut bacteria

02/17/2017 08:00:19 AM

The human large bowel ("gut") is colonised by an extremely dense population of bacteria, collectively termed the microbiota or "gut flora."Recent research indicates that the microbiota is important for human health and nutrition and has been ...

Good Practice Guidelines for Blood Establishments

02/15/2017 07:00:11 AM

EU directive integrates Council of Europe Good Practice Guidelines for blood establishmentsGood Practice Guidelines have been prepared through co-operation between the European Directorate for the Quality of Medicines & HealthCare of the Council ...

Trail vaccine for leprosy

02/14/2017 07:00:14 AM

Leprosy, also known as Hansen’s disease, is caused by the bacterium Mycobacterium leprae. These Gram-positive, rod-shaped bacteria depend greatly on their host for survival - they have lost many important metabolic genes through the process ...

Control of transmission mechanism mediated of calcium pulses

02/13/2017 07:00:03 AM

A new medical article of interest. looking at the effects of calcium ion depletion on the human cell.The abstract reads:Given the importance of calcium for good functioning of the body and knowing its involvement in signaling mechanisms and ...

Antimicrobial resistant bacteria detected in air pollution

02/12/2017 07:00:15 AM

Areas subject to air pollution contain a growing concentration of bacteria that are resistant to antimicrobials, according to a new study. Consequently, air movement may provide a new ways for their transmission.By Tim SandleThe study, highlighting ...

Model to predict how microbiomes may respond to change

02/11/2017 08:00:12 AM

Scientists studying microbiomes have created a framework for predicting how the composition of these complex microbial communities may respond to changing conditions.The review study, led by Jennifer Martiny, professor of ecology & evolutionary ...

Unique microbial photosynthesis discovered

02/10/2017 07:00:23 AM

Researchers at Washington State University have discovered a new type of cooperative photosynthesis that could be used in engineering microbial communities for waste treatment and bioenergy production.Prosthecochloris aestaurii, a green-tinged, ...

New surgical mask renders viruses harmless

02/09/2017 07:30:16 AM

Hyo-Jick Choi, a professor in the University of Alberta Department of Chemical and Materials Engineering, noticed that many people wear a simple surgical-style mask for protection during outbreaks of influenza or other potentially deadly viruses ...

Medical Device Risk – ISO 14971 Gets It Right

02/08/2017 07:00:14 AM

William Storage has written an interesting article on risk assessment. Here’s a quote from the thought provoking article: “Obvious as those may seem, defining risk in terms of hazards is surprisingly uncommon; leaving severity out of its ...

Effects of storage time and environmental exposure on soil bugs

02/07/2017 07:30:11 AM

Are soil organisms still risky after a year in the sun? International researchers placed trays of soil in and around sea containers, as well as in cupboards, to count the creatures in them every few months. They showcase some of the risks presented ...

Disinfectants: Properties, Applications and Effectiveness

02/06/2017 08:00:12 AM

A new book of interest has been published,m titled "Disinfectants: Properties, Applications and Effectiveness." The book is edited by Ana Sofia Cardoso, Cristina Maria Martins Almeida, Telma Costa Cordeiro, and Vanessa de Jesus Gaffney. The ...

Innovative Strategies for Reducing Nasal Colonization

02/05/2017 08:00:17 AM

Staphylococcus aureus(S. aureus) and methicillin resistant S. aureus (MRSA) can cause difficult-to-treat infections due to their antibiotic resistance. Approximately 90,000 people are affected yearly, and 20,000 people die from infections caused ...

Captive monkeys gain human microbiomes

02/04/2017 08:00:20 AM

To explore how a microbiome adapts to a new environment, University of Minnesota researcher Dan Knights and his colleagues turned their attention to nonhuman primates. According to Bioscience Techniques, the team examined the microbiota from ...

Scientists tissue-engineer functional part of human stomach

02/03/2017 07:30:26 AM

Scientists have used pluripotent stem cells to generate human stomach tissues in a Petri dish that produce acid and digestive enzymes. They grew tissues from the stomach's corpus/fundus region. The study comes two years after the same team generated ...

Key proteins that may make Zika so deadly

02/02/2017 07:00:32 AM

Zika virus has infected hundreds of thousands of people around the world, mostly in the Americas. In the United States and its territories, more than 38,000 Zika cases have been reported so far, most of them in Puerto Rico. There are no vaccines ...

Mathematical modeling to explain antimicrobial resistance

02/01/2017 08:00:08 AM

Modern medicine and treatments for bacterial infections and cancer have significantly increased life spans and improved quality-of-life. However, many drugs eventually fail because of the outgrowth and survival of treatment-resistant populations. ...

Some bacteria express an antibiotic-deactivating factor

01/31/2017 07:00:05 AM

Bacteria that are susceptible to antibiotics can survive when enough resistant cells around them are expressing an antibiotic-deactivating factor. This new take on how the microbial context can compromise antibiotic therapy was published by ...

Secret code language of bacteria revealed

01/30/2017 07:30:22 AM

Antibiotic resistance in pathogenic bacteria is a growing global challenge. Danish researchers have now discovered that bacteria use a code language to avoid being controlled. Understanding this code language will be paramount to developing ...

How to Implement Big Data for Pharmaceutical Supply Chain Management

01/29/2017 14:33:21 PM

Big data and predictive analytics are quickly changing the way most industries do business. By collecting all industry-related data, even the little pieces of data that might seem insignificant, companies can predict trends, find patterns and ...

Estimating time since death using necrobiome

01/29/2017 07:30:24 AM

A team led by Dr. Nathan H. Lents of the John Jay College of Criminal Justice, City University of New York (CUNY), sampled bacteria from the ear and nasal canals of 21 cadavers through several weeks of decomposition. They then analyzed the bacterial ...

How Bacteria Survive Antibiotic Treatment

01/28/2017 08:00:11 AM

Scientists around the world are working hard to win the battle against multi-resistant bacteria. A new publication from the BASP Centre, University of Copenhagen now presents how even sensitive bacteria often manage to survive antibiotic treatment ...

Gene transfer on the fungal highway

01/27/2017 07:30:33 AM

Soil bacteria use the extensively branched, thread-like structures of fungi to move around and access new food sources. In a new study, researchers have been able to demonstrate that these so-called fungal hyphae also form a hot spot for gene ...

European Pharmacopoeia 9th Edition

01/26/2017 08:00:04 AM

A new edition of the European Pharmacopeia is effective from 1st Jan 2017. The following changes have been made: Test for heavy metals have been deleted from the monographs concerned.‘Anhydrous’ has been deleted from the title of the monographs ...

Seoul viral outbreak linked to home-based rat-breeding facilities

01/25/2017 12:18:15 PM

Eight people, who shared the common factor of working at different rat-breeding facilities in two different U.S. states and who contracted Seoul virus, most likely contracted the virus from the rats.Special report by Tim Sandle:This is the outcome ...

Ph. Eur. Commission aimed to reduce animal testing

01/25/2017 08:00:20 AM

The recent adoption at its 156th session of the following texts demonstrates the Commission’s commitment to the replacement, reduction and refinement of animal tests in the quality control of medicines.Ph. Eur. General Chapter Adopted: Su ...

Assuring Data Integrity for Life Sciences (book)

01/24/2017 07:00:02 AM

A useful book has been published - 'Assuring Data Integrity for Life Sciences' - edited by Siegfried Schmitt.This new book provides a truly global perspective on data integrity and the solutions available to address this serious issue. It includes ...

Development of cleanrooms: historical review

01/23/2017 07:00:20 AM

Tim Sandle has traced the history ofcleanrooms in two part feature. Part 1 covers the early concept of clean spaces, as required for surgery, and traces these to developments immediately post-war. Part 2 will address the coming of modern cleanroom ...