Cilia: 'The bouncer' of bacteria

10/19/2017 07:00:20 AM

A new paper, from University of Southern California, elucidates the active role of cilia in regulating flow for bacteria filtering and enhancing chemical communication.The paper, published in the Proceedings of the National Academy of Sciences, ...

Microbiologist Wins International Prize for Biology

10/18/2017 08:00:05 AM

Rita Colwell, a Distinguished University Professor in the University of Maryland Institute for Advanced Computer Studies, has been named the 2017 laureate of the International Prize for Biology for her outstanding contributions to marine mi ...

How Listeria monocytogenes can survive in extreme environmental conditions

10/17/2017 07:30:17 AM

It is difficult to eliminate L. monocytogenes from post processing contamination of food production lines since this pathogen is common in various environments outside processing plants, and can endure in food processing environments. Listeria ...

New standards for cleanroom construction

10/16/2017 07:00:19 AM

Tim Sandle has written a new article for Cleanroom Technology around the subject of cleanroom construction. A new part of ISO 14644 – part 14 – came out last year which covers cleanroom equipment specification. Tim Sandle looks at why it ...

Solutions for the automated infeed and loading of medical products

10/15/2017 06:00:23 AM

Wolfertschwenden– Presentations from MULTIVAC at this year's Compamed will include solutions for the automated infeed and loading of medical products within the packaging procedure. In addition to a syringe infeed system for loading ...

Klebsiella species share drug resistance genes

10/14/2017 07:30:27 AM

Three different species of Klebsiella bacteriacan cause life-threatening infections in hospital patients and that all three share genes that confer resistance to the most commonly used antibiotics, new research shows. The study improves physicians' ...

WHO Specifications for Pharmaceutical Preparations

10/13/2017 07:00:14 AM

The World Health Organization (WHO) Expert Committee on Specifications for Pharmaceutical Preparations meets now annually and their reports (Technical Report Series) include all adopted guidelines in the form of Annexes. The 51streport has now ...

Microbial Identification strategy for pharmaceutical microbiology

10/12/2017 08:00:03 AM

Microbial identification represents an important part of the microbiology function. This includes screening products for objectionable organisms, profiling the environmental microbiota, and investigating out-of-limits events with a view to assigning ...

A new estimate of biodiversity on Earth

10/11/2017 07:30:30 AM

To date, about 1.5 million species have been formally described in the scientific literature, most of them insects. Proportionally, bacteria comprise less than 1% of all described species.Scientists generally agree that many more species exist ...

A Guide to Applying the Four Pillars of ICH Q10

10/10/2017 06:00:04 AM

A white paper of interest from Pharmaceutical Manufacturing:This White Paper will detail not only the applications of the four pillars and their corresponding QMS applications, but also additional QMS functions that help to ensure ICH Q10 c ...

Sterilization: Practical Approaches

10/09/2017 07:30:00 AM

A new e-book has been published: Sterilization: Practical Approaches offers practical approaches to sterility testing, Gamma Irradiation for single use disposables, sterilization using EtO and dry heat, ophthalmic preparations and contamination ...

Digital colony counters making microbiology easier

10/08/2017 07:30:22 AM

For microbiologists the process of counting bacterial colonies can be tedious and mistakes can happen. Laboratory managers are turning attention to automated, digital devices to streamline processes.Technology review by Tim SandleThe ‘lean’ ...

Understanding Biosafety Levels

10/07/2017 07:00:11 AM

The handling of any biological agent requires an understanding of the agent and the risk of exposure to personnel, the facility, and the environment. The U.S. CDC and the NIH have used risk assessment to develop four ascending biosafety levels ...

Europe and U.S. Regulators Increase Cooperation on Inspections

10/06/2017 07:00:08 AM

The European Commission, the FDA, and the European Medicines Agency (EMA) have signed a new confidentiality agreement that allows regulators on both sides of the Atlantic to share non-public and commercially confidential information, including ...

Epigenetic drugs show promise as antivirals

10/05/2017 08:00:03 AM

Some epigenetic pharmaceuticals have the potential to be used as broad spectrum antivirals, according to a new study. The study demonstrated that histone methyltransferases EZH2/1 inhibitors, which are being used in cancer clinical trials, have ...

Matrix Approach for the Qualification of a Pharmaceutical Facility Autoclave

10/04/2017 07:30:12 AM

The validation and verification of the sterilization process requires careful planning, and this includes selection of the loads (pre-defined configurations of items to be sterilized). For the validation or qualification approach different ...

Understanding antibiotic resistance

10/03/2017 07:30:25 AM

Researchers have uncovered new insights into how bacteria respond to stress. When deprived of nutrients, strains of the bacterium Streptococcus pneumoniae mount a coordinated defense. When exposed to antibiotics, the bacterial response is highly ...

Sterilization: Establishing the Process

10/02/2017 08:00:09 AM

A new e-book has been published: Sterilization: Establishing the Process discusses compliance, regulatory inspections, containment system sterility, test failure investigations and many other basics.The content is:Compliance Aspects of Sterility ...

The Internet of Things (IoT) Within The Laboratory

10/01/2017 08:00:07 AM

Getting real value out of IoT it can be viewed as a ‘perfect storm’ in the sense that it presents “a rare combination of circumstances with the potential to result in an event of unusual magnitude.” IoT can be defined as physical objects ...

Fungi are key players of the deep biosphere

09/30/2017 07:30:09 AM

In addition to the life on the surface of Earth and in its oceans, ecosystems have evolved deep under us in a realm coined the "deep biosphere" which stretches several kilometers down into the bedrock. Down there, the conditions are harsh and ...

Study contradicts widely held belief on length of antibiotics use

09/29/2017 07:30:13 AM

A new study emerged, published in the BMJ has countered this by suggesting that this direction is not based on evidence.The study actively argues against the “complete the course” mantra, suggesting that patients should instead stop taking ...

Bacteria busting detergent

09/28/2017 07:00:27 AM

Advertorial:There seems to be no shortage of ways to stay fresh and clean these days—in recent news, everything from MIT biofabrics that leverage living bacteria, to T-shirts made from coffee beans, are claiming to answer the ever-growing ...

Yeast helps hunt for new medicines

09/27/2017 07:00:03 AM

Scientists have developed a new way to predict potentially useful drugs from a pool of undefined chemicals. They were able to more quickly identify leads that could be used to treat a range of diseases, from infections, to cancer to Alzheimer's. ...

Written procedures for new applicants for Wholesale Dealer Authorisations

09/26/2017 07:30:23 AM

The MHRA blog contains an article of interest for those involved with regulatory activities. The blog is titled “Creating written procedures for new applicants for Wholesale Dealer Authorisations (WDA)”, and it is written by Steve Todd. ...

Community acquired pneumonia in children

09/25/2017 08:00:00 AM

Pneumonia in children of all age groups has a strong association with morbidity. This highlights the importance of studying the clinical and diagnostic aspects of community-acquired pneumonia. For those suffering from pneumonia, general biological ...

How bacteria maintain and recover their shape

09/24/2017 07:30:15 AM

Bacteria have an extraordinary ability to maintain and recover their morphology even after being twisted out of shape. Shape plays an important role in how bacteria infiltrate and attack cells in the body. The helical shape of Helicobacter pylori, ...

How S. aureus spreads resistance to antibiotics

09/23/2017 08:00:19 AM

Infection by S. aureus is a serious threat in hospitals worldwide. Now, scientists have identified a key component of the machinery that allows Staphylococcus aureus to transfer genes that confer antibiotic resistance. Halting the spread of ...

Key Factors for Producing Error Free Pharma Packaging

09/22/2017 07:30:10 AM

The pharmaceutical industry stands for one of the fastest growing and the most profitable industries in the world. An increase in sales and growth of the work amount, apart from the high profit, can bring some unwanted problems and challenges ...

Analysis Of FDA Warning Letters

09/21/2017 07:30:04 AM

Failures in data governance and data integrity have been more prominent in health authority enforcement actions in the past few years. This is the focus of a review of FDA warning letters and data integrity concerns, conducted by Barbara Unger, ...

Cases of superbug Clostridium difficile increase

09/20/2017 13:40:17 PM

The most troubling cases of C. difficile infection, termed multiple recurring C. difficile infections (mrCDI), are becoming more common, according to a new university research study.The study comes from the University of Pennsylvania School ...

GLP Inspections metrics reflections

09/19/2017 14:10:13 PM

An MHRA blog post by Martin Reed looks at collation of the 2015 inspection metrics data.According to Reed, these data have "highlighted some common themes which I am going to illustrate by sharing some examples with you. All of the situations ...

Design and control of pharmaceutical water systems

09/18/2017 08:00:04 AM

Water-borne microorganisms are ubiquitous and varied in their ability to survive and grow under different conditions. Therefore, an out-of-control water system can cause harm to the patient or adulterate pharmaceutical products. Purification ...

Magnetized viruses attack harmful bacteria

09/17/2017 08:00:04 AM

Antibacterial phages combined with magnetic nanoparticle clusters effectively kill infectious bacteria found in water treatment systems. A weak magnetic field draws the clusters into biofilms that protect the bacteria and break them up so the ...

Plan for the introduction of the safety features on medicinal packaging

09/16/2017 08:00:03 AM

The European Medicines Agency (EMA) has issued a new guidance document titled “Implementation plan for the introduction of the safety features on the packaging of centrally authorized medicinal products for human use.”Certain aspects of ...

Good clinical practice inspection metrics

09/15/2017 07:00:08 AM

The MHRA has published the 1st April 2015 to 31st March 2016 GCP Inspection metrics report. During the metrics period a total of 102 GCP Inspections were undertaken by the MHRA GCP Inspectorate.The full report can be accessed here: MHRAPosted ...

British Pharmacopoeia 2018 now available

09/14/2017 07:30:01 AM

The BP 2018 comprises of more than 250 new or amended monographs, including those from the European Pharmacopeia. The British Pharmacopoeia (BP) 2018 supersedes the BP 2017 and becomes legally effective on 1 January 2018. This edition incorporates ...

World Sepsis Day

09/13/2017 07:00:09 AM

Today is World Sepsis Day.Here are some key points from World Sepsis Day 2017What is sepsis?Sepsis is a life-threatening condition that occurs when the body's response to an infection damages its own tissues and organs. Instead of local inflammation ...

Regulators raise concern with rapid method validation

09/12/2017 08:00:12 AM

In July 2017 Sage Products Inc. received a warning letter from the U.S. Food and Drug Administration (FDA). Within the warning letter was a concern about the implementation of rapid microbiological method, where the method had been used to replace ...

The path towards international harmonization of cleanrooms

09/11/2017 07:00:02 AM

Cleanrooms are an established and expected feature of healthcare and pharmaceutical operations; however, their development has been gradual and the origins, in terms of the idea of a ‘clean space’ date back several hundred years. In the ...

Battle-plan blueprints for attacking disease-causing bacteria

09/10/2017 07:30:34 AM

The scientists, led by Fellow Emeritus in Trinity's School of Biochemistry and Immunology, Professor Martin Caffrey, used next-gen X-ray crystallography techniques to 'look under the bacterial bonnet' and produce a molecular blueprint that may ...

New mechanism for bacterial division discovered in some bacteria

09/09/2017 07:00:00 AM

Scientists show how some pathogenic bacteria -- such as the mycobacteria that cause tuberculosis -- use a previously unknown mechanism to coordinate their division. The discovery could help develop new ways to fight them.Most rod-shaped bacteria ...

How big bacteria can grow depends on how much fat they can make

09/08/2017 07:30:01 AM

Bacterial cells in carbon-rich media grow twice as big as those in carbon-poor media. New research shows they can grow big, however, only if they can make fats with the carbon. The membrane that defines the boundary between the inside and outside ...

Antibiotic resistance linked to household disinfectant triclosan

09/07/2017 14:41:05 PM

British scientists have found a connection between a significant mechanism of antibiotic resistance to the disinfectant triclosan. This chemical is found in many common domestic products. A report by Tim Sandle.The research comes from two research ...

Products for Microbiological Control

09/07/2017 14:34:05 PM

Benefit from Sartorius’ long-standing expertise in microbiological quality control while increasing performance and enhancing your workflows. To help improve the safety of quality-critical processes, we offer premium products for microbial ...

Ebola detected in semen of survivors two years after infection

09/07/2017 08:00:13 AM

Ebola virus RNA can persist in the semen of survivors more than two years after the onset of infection researchers at the University of North Carolina at Chapel Hill have found. The research team, which included investigators from Ohio-based ...

MRSA survival chances predicted by DNA sequencing

09/06/2017 08:00:11 AM

Sequencing the DNA of the MRSA superbug can accurately identify patients most at risk of death and could help medics develop new treatments as we move towards personalised medicine. MRSA is a Staphylococcus aureus bacterium that has become resistant ...

Unknown virus discovered in 'throwaway' DNA

09/05/2017 07:30:32 AM

Finding new viruses has historically not been an easy process. Cells do not grow on their own, so must be cultured in a laboratory before they can be analysed, which involves months of work. But the Oxford research represents a massive opportunity ...

Fungi associated with sandstorms

09/04/2017 07:00:19 AM

A new research paper of interest:Background: The impact of sandstorm dust events on local air quality and public health are becoming a greater concern in the Kingdom of Saudi Arabia. Among sandstorm dust particles, airborne fungal spores cause ...

Data-Driven Risk Management For Quality By Design

09/03/2017 07:30:00 AM

The main hope of ICH Q8-Q10 pertaining to operational excellence is to enable (bio)pharmaceutical companies to achieve product realization. The goal is to do so by establishing and maintaining a state of control and facilitating continual i ...

Alternative antimicrobial compounds from wastewater

09/02/2017 08:00:14 AM

Biosurfactants are compounds produced naturally by bacteria, fungi or yeasts and they have been commercially utilised in shampoos, shower gels, and household cleaning products. They are also used in food, agriculture, cosmetic and medical industries ...

Yeast helps hunt for new medicines

09/01/2017 08:30:43 AM

Scientists have developed a new way to predict potentially useful drugs from a pool of undefined chemicals. They were able to more quickly identify leads that could be used to treat a range of diseases, from infections, to cancer to Alzheimer's. ...

Ebola burial teams saved thousands of lives

08/31/2017 07:30:00 AM

A new study, reviewing the actions taken in response to the 2014-2015 West African Ebola crisis, has found the burial practices conducted by medical staff were highly effective in reducing the infection spread.he Ebola crisis, which has ravaged ...

New paradigm for advancing research on beneficial microbes

08/30/2017 08:30:09 AM

While beneficial microbes are becoming a more common tool in agriculture, their effectiveness in the field is severely blunted thanks to real-world environmental stressors like heat and drought, competition with other microbes, and interactions ...

New tool to distinguish between viral & bacterial infections

08/29/2017 08:00:22 AM

Antibiotics are lifesaving drugs, but overuse is leading to antibiotic resistance, one of the world's most pressing health threats. Scientists identified 11 genetic markers in blood that accurately distinguished between viral and bacterial ...

Pseudomonas aeruginosa: Assessing patient risk

08/28/2017 07:00:02 AM

A new research paper of interest has been published:Introduction: Pseudomonas aeruginosa is an important pathogen in nosocomial infections and developed typing techniques are essential allowing researchers to understanding hospital epidemiology. ...

Model for hepatitis C could pave the way for a vaccine

08/27/2017 07:00:08 AM

Charlie Rice, the Maurice R. and Corinne P. Greenberg Professor in Virology at The Rockefeller University, has been working for decades to develop just that; in fact, his previous research lead to the development of the cure for hepatitis C ...

Living together brings couples' microbiomes together

08/26/2017 07:30:00 AM

Couples who live together share many things: Bedrooms, bathrooms, food, and even bacteria. After analyzing skin microbiomes from cohabitating couples, microbial ecologists found that people who live together significantly influence the microbial ...

How CRISPR proteins find their target

08/25/2017 07:00:00 AM

In addition to the Cas9 protein that bacteria use to bind and snip DNA, bacteria have other Cas proteins that know where to insert that viral DNA into the CRISPR region to remember which viruses have attacked and mount a defense. A research ...

Calcium key to fighting a dangerous hospital infection

08/24/2017 07:30:21 AM

The discovery, made in research laboratories at the University of Michigan Medical School and the U.S. Food and Drug Administration, is published in the online journal PLoS Pathogens. It helps solve a key mystery about C. diff: What triggers ...

Aging pharmaceutical facilities

08/23/2017 07:30:03 AM

The aging facility presents various microbiological contamination risks (and some more recent pharmaceutical product recalls associated with microbial contamination have related to older facilities). These risks include:Poor facility manage ...

Bacteria never swim alone

08/22/2017 08:00:02 AM

Flocking behaviour in animals seemingly arises spontaneously in a group of independent individuals without a clear leader. This behaviour occurs among all types of organisms, from bacteria to people. One hypothesis, therefore, is that there ...

Accidental discoveries that revolutionised medicine

08/21/2017 17:43:33 PM

Today, medical research takes up to 10 years to complete with thousands of hours of research taking place to perfect the drug, but that hasn’t always been the case. In fact, many medicines that we take for granted today are actually the result ...

Amazing drugs in development (infographic)

08/20/2017 17:49:38 PM

At any one time, there are hundreds of drugs being developed around the world. Some of them could change the way we treat conditions such as lung cancer and asthma. Here are six drugs currently in development that have a real chance of finding ...

Key Challenges of Packaging and Labeling in Pharma Products

08/20/2017 12:49:08 PM

The Dire Issues of Barcodes and labelingBarcodes are very standard tools that have been around for decades. Barcodes were first introduced and used in the Pharmaceutical Industry in the 1970’s. Many people do not truly know the critical role ...

FDA cGMP for Medical Gases

08/20/2017 07:30:17 AM

New draft FDA guidance of interest "Current Good Manufacturing Practice for Medical Gases Guidance for Industry."The introduction to the document reads: "This guidance is intended to assist manufacturers of medical gases in complying with ...

Bacteria on surfaces and strength of adhesion

08/19/2017 06:30:15 AM

Scientists have developed a method with which they can measure the contact area between a bacterium and the surface it is 'sitting' on. Interestingly a large contact area does not necessarily mean a large adhesive force. It turns out that specific ...

Cranberries may aid the gut microbiome

08/18/2017 08:00:07 AM

Using the model beneficial bacterium bifidobacteria, researchers tested the hypothesis that cranberries might be a candidate for a new supplement to boost gut health. Bifidobacteria are found in adults to some degree but the highest concentrations ...

Studying fungi to keep space travelers safe

08/17/2017 07:30:05 AM

Human presence in closed habitats that may one day be used to explore other planets is associated with changes in the composition of the fungal community - the mycobiome - that grows on surfaces inside the habitat, according to a new study.Dr ...

Helium ions reveal how viruses attack bacteria

08/16/2017 07:30:20 AM

Bacteria and viruses can be imaged with helium ions in contrast to electrons which are the standard workhorse in nanoscale microscopy, report scientists. Helium ions, being more massive than electrons, can be focused to a much tighter spot down ...

Cleanroom summit

08/15/2017 07:00:37 AM

The Cleanroom Management Summit would like to highlight Annex 1 compliance, audit readiness and isolator technology as the essential topics for the pharmaceutical and healthcare industries. Included in the Summit’s Agenda they will result ...

Validation and Assessment of Computerized System Software in a Pharmaceutical Facility

08/14/2017 14:54:43 PM

Validation is an established approach within pharmaceuticals and healthcare, and the principles of validation extend to computerized systems. Validation concerns establishing documented evidence designed to produce a high degree of assurance ...

Pharmig News

08/13/2017 07:35:41 AM

The latest edition of Pharmig News has been published. This is edition #68.Inside the issue is part 1 of Pharmig’s survey of best practices for culture media, a regulatory news round-up, the chairman’s perspective, review of ‘Making P ...

FDA unveils plan to eliminate orphan designation backlog

08/13/2017 07:00:15 AM

U.S. Food and Drug Administration unveiled a strategic plan to eliminate the agency’s existing orphan designation request backlog and ensure continued timely response to all new requests for designation with firm deadlines. The agency’s ...

Pharmig News #67

08/13/2017 06:37:46 AM

Pharmig Newsletter #67 by Tim Sandle on ScribdPosted by Dr. Tim SandlePharmaceutical Microbiology (c) Dr Tim Sandle http://www.pharmamicroresources.com

Single Entity Injectable Drug Products

08/12/2017 08:00:21 AM

The FDA is requiring the removal of ratio expressions of strength from the labeling of single-entity injectable drug products (i.e., drug products that contain only one active ingredient) and replacement with the amount per unit of volume (e.g., ...

Designing cleanrooms for particulate control (Turkish)

08/11/2017 08:00:20 AM

Tim Sandle has written an article for the Turkish Cleanroom News publication - Designing cleanrooms for particulate control (Turkish: Parçac?k kontrolü için temiz oda tasar?m?).The reference is:Sandle, T. (2017) Designing cleanrooms for ...

Supply Chain Security Toolkit for Medical Products

08/10/2017 07:30:23 AM

News from the FDA:Protecting the integrity of the medical product supply chain is complex and requires a global approach. FDA led a collaboration within Asia Pacific Economic Cooperation (APEC) economies to create a Supply Chain Security Toolkit ...

GMP Short Notice and Unannounced Inspections

08/09/2017 07:30:13 AM

An interesting blog post from the UK MHRA:The Human Medicines Regulations 2012 as amended; regulation 325 ‘Rights of Entry’ states that an inspector may at any reasonable time enter premises. This allows for the MHRA to perform inspections ...

Guidance for stem cell therapies in animals

08/08/2017 08:00:11 AM

The European Medicines Agency (EMA) has published the first ever guidance document for stem cell therapies in animals. The guidance addresses concerns raised by manufacturers and authorities in regard to the sterility (absence of bacteria, fungi ...

New book: Aseptic and Sterile Processing: Control, Compliance and Future Trends

08/07/2017 15:20:37 PM

New book: Aseptic and Sterile Processing: Control, Compliance and Future Trends. Edited by Tim Sandle and Edward C. Tidswell.Sterile medical products comprise of medical devices, drugs, and biologics. Some are completed  by a terminal ste ...

Santitization of Pharmaceutical Facilities

08/07/2017 08:00:10 AM

A new paper on cleaning and disinfecting pharmaceutical and healthcare facilities has been published. Here is the abstract:Maintaining environmental control including microbiological contamination in a pharmaceutical manufacturing environment ...

Teixobactin - new antibiotic update

08/06/2017 07:30:14 AM

Scientists have produced new, effective and simplified forms of teixobactin - a new generation antibiotic which defeats multi-drug resistant infections such as MRSA - as part of a pioneering research effort to tackle antimicrobial resistance.The ...

EU report on antimicrobial resistance

08/05/2017 08:00:09 AM

Following a top level EU report showing antimicrobial resistance (AMR) remains high, Professor Mike Catchpole, Chief Scientist at the European Centre for Disease Prevention and Control (ECDC), has warned that stricter use of antibiotics is ...

The world is underprepared for infectious diseases

08/04/2017 08:00:06 AM

A team of international experts has highlighted how the world remains ‘grossly underprepared’ for infectious disease outbreaks, which are likely to become more frequent in future decades.Led by Professor Suerie Moon at the Graduate Institute ...

New test measures how long it takes to kill bacteria

08/03/2017 07:00:21 AM

A simple new method has been developed for measuring the time it takes to kill a bacterial population could improve the ability of clinicians to effectively treat antimicrobial-tolerant strains that are on the path to becoming resistant.According ...

Bacterial classification remains elusive

08/02/2017 07:30:08 AM

New research from Dartmouth College raises questions over how scientists should interpret observed groupings of bacteria. The study advises caution with the assumption that bacterial clusters are always a result of ecological and genetic forces.The ...

Gut bacteria play a key role in regulating abdominal pain

08/01/2017 15:18:32 PM

Visceral pain is a global term used to describe pain originating from the internal organs of the body, which affects a significant proportion of the population and is a common feature of functional gastrointestinal disorders such as irritable ...

The pathologic appendix

07/31/2017 14:04:58 PM

Antonella Chesca and Tim Sandle have written an article looking at the pathologic appendix.Here is the abstract:Appendix pathology brings together different forms and is found in different age segments. Most susceptible to disease are children. ...

Battling infections with bioelectricity

07/30/2017 08:00:17 AM

Is the answer to fighting pathogens connected with bioelectricity? Promising new research suggest this is possible by using drugs to changing electrical charge of cells. Studies have been performed in frogs.What is remarkable about the studies ...

Bacterial pathogens interact to cause disease

07/29/2017 08:00:11 AM

New methodology allowed researchers to more easily investigate mechanisms of infection and provide new insight into how pathogens can work together to cause disease. Using the new tool, researchers confirmed a safer model for study of Brucella ...

Aseptic and Sterile Processing: Control, Compliance and Future Trends

07/28/2017 15:39:23 PM

The Aseptic and Sterile Processing: Control, Compliance and Future Trends is the most important text discussing aseptic and sterile manufacturing that has been published in the last decade! This text looks at both today and tomorrow in regard ...

New approach to battle drug-resistant bacteria

07/28/2017 07:30:05 AM

Researchers at University of Utah Health have developed a rapid screening method to identify beneficial pairs of existing FDA-approved drugs to combat multi-drug resistant (MDR) bacterial infections. The microbiologists analyzed a bacterial ...

EMA issues guidance document in preparation for Brexit

07/27/2017 06:30:36 AM

The European Medicines Agency (EMA) and the European Commission have published guidance to help pharmaceutical companies prepare for the United Kingdom’s withdrawal from the European Union.The question-and-answer document contains information ...

Moist-heat sterilization of blood bags

07/26/2017 07:30:18 AM

The most suitable type of autoclaves for sterilizing blood bag systems are autoclaves in which sterilizing medium is a mixture of steam and air. This method, one of the counter pressure types of sterilization, is also called ‘air-over-steam’. ...

High prevalence of CRE in Washington, D.C.

07/25/2017 07:30:28 AM

Carbapenem-resistant Enterobacteriaceae (CRE), a family of highly pathogenic antibiotic-resistant organisms, are endemic across Washington, D.C. healthcare facilities, with 5.2 percent of inpatients testing positive for the bacteria, according ...

Chronic obstructive pulmonary disease

07/24/2017 07:30:05 AM

Antonella Chesca and Tim Sandle have written an article looking at chronic obstructive pulmonary disease.Here is the abstract:The present study refers to the exploration of the respiratory function of patients who presented acute symptoms of ...

New antibiotic effective against drug-resistant bacteria

07/23/2017 07:00:27 AM

Scientists have discovered a new antibiotic effective against drug-resistant bacteria: pseudouridimycin. The new antibiotic is produced by a microbe found in a soil sample collected in Italy and was discovered by screening microbes from soil ...

Bacteria from hot springs solve mystery of metabolism

07/22/2017 07:30:12 AM

Combustion is often a rapid process, like fire. How can our cells control the burning process so well? The question has long puzzled researchers. Using bacteria from hot springs, researchers from Stockholm University now have the answer.Light ...

New health and safety standard

07/21/2017 07:30:22 AM

A new International Standard due out early next year – ISO 45001. This is ISO’s first standard for occupational health and safety management systems.According to ISO: “ISO 45001, Occupational health and safety management systems – R ...

European Pharmacopoeia revises Biological Indicator Chapter

07/20/2017 07:00:00 AM

The general chapter in the European Pharmacopoeia (5.1.2) relating to biological indicators has undergone a significant revision. The new version has been issued with the release of supplement 9.2 to the 9th edition of the pharmacopoeia (1). ...