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New TB drug candidates developed from soil bacteria

03/23/2017 08:30:27 AM

A new treatment for tuberculosis (TB) is set to be developed using compounds derived from bacteria that live in soil -- according an international collaboration of researchers, including the University of Warwick.The group looked at soil bacteria ...

10 Healthy Eating Tips for the Student

03/22/2017 08:30:22 AM

College students must know how to maintain their body healthily and strong. Their food diet should be well-planned, and they should take their food in time. Eating is compulsory for all of us. But for students, it is more than necessary. They ...

TB Alliance Calls on WHO to Add Tuberculosis to List of Critical Group of Bacteria

03/21/2017 08:30:42 AM

TB Alliance and the broader TB community urge that the World Health Organization (WHO) add Mycobacterium tuberculosis to the critical group within the list of drug-resistant bacteria identified as urgent priorities for research and developm ...

National Poison Prevention Week

03/20/2017 08:30:02 AM

In recognition of National Poison Prevention Week (March 19-25), the National Capital Poison Center urges all parents to take 2 minutes to learn how to prevent and respond to a poison emergency. More than a million poison exposures occur every ...

Which Medicine For Ed Has The Lowest Number Of Side Effects?

03/19/2017 13:04:32 PM

Erectile dysfunction (ED) is pretty common among men with almost half of men between the ages 40 to 70 have some kind of erectile problems.  The Journal of the American Medical Association reported that 7 percent of men aged 18 to 29 and 9 ...

New way to classify viruses based on structure

03/19/2017 09:00:26 AM

Professor Robert Sinclair at the Okinawa Institute of Science and Technology Graduate University (OIST) and Professor Dennis Bamford and Dr. Janne Ravantti from the University of Helsinki have found new evidence to support a classification system ...

Novel genetic switch boosts bacteria cells' production of useful chemicals

03/18/2017 08:30:19 AM

MIT chemical engineers have designed a novel genetic switch that allows them to dramatically boost bacteria's production of useful chemicals by shutting down competing metabolic pathways in the cells.Researchers have been trying to engineer ...

Gut inflammation controlled by changing bacterial balance

03/17/2017 08:00:38 AM

Numerous human diseases, including inflammatory bowel disease, diabetes and autism spectrum disorders have been linked to abnormal gut microbial communities, or microbiomes, but an open question is whether these altered microbiomes are drivers ...

Commonly used pain relievers have added benefit of fighting bacterial infection

03/16/2017 08:30:17 AM

Some commonly used drugs that combat aches and pains, fever, and inflammation are also thought to have the ability to kill bacteria. New research appearing online on March 13 in the Cell Press journal Chemistry & Biology reveals that these drugs, ...

Rainbow dyes add greater precision to fight against 'superbugs'

03/15/2017 08:30:10 AM

The discovery, made possible through a revolutionary method used to color bacterial cell walls developed at IU, is an important step forward in research on bacterial growth and could inform efforts to develop drugs that combat antibiotic-resistant ...

Crosstalk between intestinal microbes and immune system

03/14/2017 08:30:24 AM

The human gut is home to some 100 trillion bacteria, comprising between 250 and 500 species. This astounding array of organisms, collectively known as the gut microbiome, is a powerful regulator of disease and health and has been implicated ...

Sleepy bacteria evolve to resist antibiotics

03/13/2017 09:00:15 AM

Antibiotic resistance is a major and growing problem worldwide. According to the World Health Organization, antibiotic resistance is rising to dangerously high levels in all parts of the world, and new resistance mechanisms are emerging and ...

Is Scott Gottlieb the next FDA Commissioner?

03/13/2017 08:30:46 AM

Scott Gottlieb is President Donald Trump’s choice to lead the agency, according to Bloomberg sources at the White House.Gottlieb, a former deputy commissioner of the FDA under George W. Bush, will look to cut th red tape at the FDA, enabling ...

An Analysis Of FDA FY2016 Drug GMP Warning Letters

03/12/2017 09:00:30 AM

Pharmaceutical on-line has published a useful overview of FDA warning lettersissued in 2016. This comes from Barbara Unger, Unger Consulting Inc.Here are the headline trends:The number of drug GMP warning letters issued more than doubled over ...

Bacteria turn a tick's gut microbes against itself

03/11/2017 08:00:08 AM

Before infecting humans, tick-borne bacteria or viruses first have to get past a tick's defenses to colonize it. How this occurs is not well understood. To investigate, Yale researchers studied a model of the second-most-common tick-borne infection ...

Understanding Airlocks for cGMP Facilities

03/10/2017 08:00:24 AM

The use of airlocks is a principle that is well-established in the design of cGMP facilities. Despite the apparent simplicity of inserting small rooms into the plan of a pharmaceutical manufacturing facility, there is confusion regarding their ...

Recall Report

03/09/2017 15:13:05 PM

A new website of interest called Recall Report:A recall occurs when a medication or product is faulty or has side effects so severe that it becomes potentially dangerous to human health. Recalls happen for a number of reasons, including faulty ...

How to Safely Handle Compressed Gas Cylinders

03/09/2017 08:00:14 AM

The hazards involved in compressed gas use run the gamut from oxygen displacement (inert gas use), fires, explosions, and toxic exposures to the physical hazards of high pressurization. So in this issue, the Safety Guys offer some tips on accident ...

How to gown effectively (video) - part 2

03/08/2017 08:00:24 AM

Here is part 2 of our how to gown properly when entering cleanrooms videos.Practical workshop on good cleanroom gowning from Simon Fiala – Key Account Manager, COMPREI Reinraum. This focuses on technique # 2 (see the first video for an alternative ...

How to gown effectively (video) - part 1

03/07/2017 14:14:07 PM

Effective gowning is an important of contamination control, given that people are the biggest source of contamination in pharmaceutical facilities. To aid good gowning, we're providing two videos showing effective gowning techniques.The first ...

A Closer Look at the Right to Try Act for the Terminally Ill

03/06/2017 07:00:21 AM

There are hundreds of different investigational drugs that are in various phases of clinical trials all over the world. Until they’ve been cleared to be marketed to the public, they are only available in very limited clinical trials. While ...

Vitamin B12 and microbial growth

03/05/2017 07:30:19 AM

Scientists have found more evidence that vitamin B12, a substance produced by only a few organisms but needed by nearly all of them, wields great power in the microbial world. The findings lend credence to the idea that B12 helps shape microbial ...

How to Safely Handle Compressed Gas Cylinders

03/04/2017 08:00:19 AM

The hazards involved in compressed gas use run the gamut from oxygen displacement (inert gas use), fires, explosions, and toxic exposures to the physical hazards of high pressurization. So in this issue, the Safety Guys offer some tips on accident ...

The Science Behind the Detox Fad

03/03/2017 16:28:40 PM

A guest post By Helen Vector.Detox and detoxification have become the latest buzzwords in the diet industry fixated with convincing people (mostly women) that they have found a quick fix that will help them to lose weight fast. We now detox ...

Identifying bacteria using a flow cytometer

03/03/2017 07:30:11 AM

A new, easy-to-adapt and inexpensive analytical procedure has been developed by researchers from the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw. The main role is played by innovative bioconjugates -- luminescent, ...

European and US regulators agree on mutual recognition of inspections

03/02/2017 13:58:32 PM

Important news for those who work in organizations that regularly receive both U.S. FDA and European medicines agency inspectors. This has been a long time coming...a new transatlantic agreement is now in place, designed to will help to make ...

Evidence of the bacterial transfer during space missions

03/02/2017 08:00:35 AM

Most modern organisms require specific conditions to survive: liquid water, oxygen, moderate temperatures, stable aboveground air pressure, and low-level radiation exposure. However, not all terrestrial organisms live harmoniously under such ...

Bacteria inspire synthetic catalysts

03/01/2017 08:00:08 AM

Using a natural catalyst from bacteria for inspiration, researchers have now reported the fastest synthetic catalysts to date for hydrogen production-- producing 45 million hydrogen molecules per second.The chemical bonds in hydrogen gas, for ...

How viruses communicate

02/28/2017 08:00:06 AM

Viruses have been found to communicate with one another, leaving short “posts” for kin and descendants. The messages help the viruses reading them decide how to proceed with the process of infection, according to research.Many viruses face ...

Clean Room Technology in ART Clinics: A Practical Guide

02/27/2017 08:00:08 AM

A new book of interest 'Clean Room Technology in ART Clinics: A Practical Guide', edited by Sandro C. Esteves, Alex C. Varghese, Kathryn C. Worrilow.Regulatory agencies worldwide have issued directives or such requirements for air quality standards ...

Bacteria turn a tick's gut microbes against itself

02/26/2017 08:00:04 AM

Before infecting humans, tick-borne bacteria or viruses first have to get past a tick's defenses to colonize it. How this occurs is not well understood. To investigate, Yale researchers studied a model of the second-most-common tick-borne infection ...

Understanding Airlocks for cGMP Facilities

02/25/2017 08:00:18 AM

The use of airlocks is a principle that is well-established in the design of cGMP facilities. Despite the apparent simplicity of inserting small rooms into the plan of a pharmaceutical manufacturing facility, there is confusion regarding their ...

An Analysis Of FDA FY2016 Drug GMP Warning Letters

02/24/2017 08:00:26 AM

Pharmaceutical on-line has published a useful overview of FDA warning letters issued in 2016. This comes from Barbara Unger, Unger Consulting Inc.Here are the headline trends:The number of drug GMP warning letters issued more than doubled over ...

Advanced Cooling Systems for Blood Product Storage Applications

02/23/2017 07:30:33 AM

Century Refrigeration announces that it designs custom, advanced cooling systems for blood product storage applications, including blood banks and laboratories. The customized nature of the solutions ensures that they are capable of the low ...

Update on Ebola Outbreak and Aftermath in West Africa

02/22/2017 15:39:53 PM

WHAT: Live-streamed panel discussion and Q&A with expert MSF medical and operations staffWHEN: Thursday, February 23, 8 p.m. Eastern Time (recording will be archived online here) WHERE: Register online here DETAILS: The Ebola outbreak that ...

Each animal species hosts a unique microbial community

02/22/2017 07:30:22 AM

Each animal species hosts its own, unique community of microbes that can significantly improve its health and fitness. This is the implication of a laboratory study that investigated four different animal groups and their associated microbiota. ...

Advances in Aseptic Blow-Fill-Seal Processing

02/21/2017 07:30:12 AM

Aseptic blow-fill-seal (B/F/S) systems for the processing of pharmaceutical liquids have experienced rapid and growing acceptance by the pharmaceutical industry over the past 20 years. This has been accelerated by enhancements made to aseptic ...

The European approach to disinfectant qualification

02/20/2017 07:30:11 AM

Tim Sandle has written an overview of the European approach to disinfectant testing for the A3P publication La Vague.Here is the introduction:Contamination control is of great importance to healthcare facilities and to pharmaceutical cleanrooms. ...

Does studying yellow fever offer Zika clues?

02/19/2017 08:00:20 AM

As cases of Zika virus increase there is considerable investigation and research into the virus. One area being looked at for clues is yellow fever virus. A second area involves the use of mouse models.By Dr. Tim SandleZika virus is a member ...

Quick Laboratory Safety Tips

02/18/2017 07:30:17 AM

There is never a better time than now (excuse the cliche) to evaluate your laboratory safety procedures. For larger facilities, this can be a daunting task but necessary nonetheless. Regardless of lab size, the team at M2 Scientifics has put ...

Insight into the functioning of human gut bacteria

02/17/2017 08:00:19 AM

The human large bowel ("gut") is colonised by an extremely dense population of bacteria, collectively termed the microbiota or "gut flora."Recent research indicates that the microbiota is important for human health and nutrition and has been ...

Good Practice Guidelines for Blood Establishments

02/15/2017 07:00:11 AM

EU directive integrates Council of Europe Good Practice Guidelines for blood establishmentsGood Practice Guidelines have been prepared through co-operation between the European Directorate for the Quality of Medicines & HealthCare of the Council ...

Trail vaccine for leprosy

02/14/2017 07:00:14 AM

Leprosy, also known as Hansen’s disease, is caused by the bacterium Mycobacterium leprae. These Gram-positive, rod-shaped bacteria depend greatly on their host for survival - they have lost many important metabolic genes through the process ...

Control of transmission mechanism mediated of calcium pulses

02/13/2017 07:00:03 AM

A new medical article of interest. looking at the effects of calcium ion depletion on the human cell.The abstract reads:Given the importance of calcium for good functioning of the body and knowing its involvement in signaling mechanisms and ...

Antimicrobial resistant bacteria detected in air pollution

02/12/2017 07:00:15 AM

Areas subject to air pollution contain a growing concentration of bacteria that are resistant to antimicrobials, according to a new study. Consequently, air movement may provide a new ways for their transmission.By Tim SandleThe study, highlighting ...

Model to predict how microbiomes may respond to change

02/11/2017 08:00:12 AM

Scientists studying microbiomes have created a framework for predicting how the composition of these complex microbial communities may respond to changing conditions.The review study, led by Jennifer Martiny, professor of ecology & evolutionary ...

Unique microbial photosynthesis discovered

02/10/2017 07:00:23 AM

Researchers at Washington State University have discovered a new type of cooperative photosynthesis that could be used in engineering microbial communities for waste treatment and bioenergy production.Prosthecochloris aestaurii, a green-tinged, ...

New surgical mask renders viruses harmless

02/09/2017 07:30:16 AM

Hyo-Jick Choi, a professor in the University of Alberta Department of Chemical and Materials Engineering, noticed that many people wear a simple surgical-style mask for protection during outbreaks of influenza or other potentially deadly viruses ...

Medical Device Risk – ISO 14971 Gets It Right

02/08/2017 07:00:14 AM

William Storage has written an interesting article on risk assessment. Here’s a quote from the thought provoking article: “Obvious as those may seem, defining risk in terms of hazards is surprisingly uncommon; leaving severity out of its ...

Effects of storage time and environmental exposure on soil bugs

02/07/2017 07:30:11 AM

Are soil organisms still risky after a year in the sun? International researchers placed trays of soil in and around sea containers, as well as in cupboards, to count the creatures in them every few months. They showcase some of the risks presented ...

Disinfectants: Properties, Applications and Effectiveness

02/06/2017 08:00:12 AM

A new book of interest has been published,m titled "Disinfectants: Properties, Applications and Effectiveness." The book is edited by Ana Sofia Cardoso, Cristina Maria Martins Almeida, Telma Costa Cordeiro, and Vanessa de Jesus Gaffney. The ...

Innovative Strategies for Reducing Nasal Colonization

02/05/2017 08:00:17 AM

Staphylococcus aureus(S. aureus) and methicillin resistant S. aureus (MRSA) can cause difficult-to-treat infections due to their antibiotic resistance. Approximately 90,000 people are affected yearly, and 20,000 people die from infections caused ...

Captive monkeys gain human microbiomes

02/04/2017 08:00:20 AM

To explore how a microbiome adapts to a new environment, University of Minnesota researcher Dan Knights and his colleagues turned their attention to nonhuman primates. According to Bioscience Techniques, the team examined the microbiota from ...

Scientists tissue-engineer functional part of human stomach

02/03/2017 07:30:26 AM

Scientists have used pluripotent stem cells to generate human stomach tissues in a Petri dish that produce acid and digestive enzymes. They grew tissues from the stomach's corpus/fundus region. The study comes two years after the same team generated ...

Key proteins that may make Zika so deadly

02/02/2017 07:00:32 AM

Zika virus has infected hundreds of thousands of people around the world, mostly in the Americas. In the United States and its territories, more than 38,000 Zika cases have been reported so far, most of them in Puerto Rico. There are no vaccines ...

Mathematical modeling to explain antimicrobial resistance

02/01/2017 08:00:08 AM

Modern medicine and treatments for bacterial infections and cancer have significantly increased life spans and improved quality-of-life. However, many drugs eventually fail because of the outgrowth and survival of treatment-resistant populations. ...

Some bacteria express an antibiotic-deactivating factor

01/31/2017 07:00:05 AM

Bacteria that are susceptible to antibiotics can survive when enough resistant cells around them are expressing an antibiotic-deactivating factor. This new take on how the microbial context can compromise antibiotic therapy was published by ...

Secret code language of bacteria revealed

01/30/2017 07:30:22 AM

Antibiotic resistance in pathogenic bacteria is a growing global challenge. Danish researchers have now discovered that bacteria use a code language to avoid being controlled. Understanding this code language will be paramount to developing ...

How to Implement Big Data for Pharmaceutical Supply Chain Management

01/29/2017 14:33:21 PM

Big data and predictive analytics are quickly changing the way most industries do business. By collecting all industry-related data, even the little pieces of data that might seem insignificant, companies can predict trends, find patterns and ...

Estimating time since death using necrobiome

01/29/2017 07:30:24 AM

A team led by Dr. Nathan H. Lents of the John Jay College of Criminal Justice, City University of New York (CUNY), sampled bacteria from the ear and nasal canals of 21 cadavers through several weeks of decomposition. They then analyzed the bacterial ...

How Bacteria Survive Antibiotic Treatment

01/28/2017 08:00:11 AM

Scientists around the world are working hard to win the battle against multi-resistant bacteria. A new publication from the BASP Centre, University of Copenhagen now presents how even sensitive bacteria often manage to survive antibiotic treatment ...

Gene transfer on the fungal highway

01/27/2017 07:30:33 AM

Soil bacteria use the extensively branched, thread-like structures of fungi to move around and access new food sources. In a new study, researchers have been able to demonstrate that these so-called fungal hyphae also form a hot spot for gene ...

European Pharmacopoeia 9th Edition

01/26/2017 08:00:04 AM

A new edition of the European Pharmacopeia is effective from 1st Jan 2017. The following changes have been made: Test for heavy metals have been deleted from the monographs concerned.‘Anhydrous’ has been deleted from the title of the monographs ...

Seoul viral outbreak linked to home-based rat-breeding facilities

01/25/2017 12:18:15 PM

Eight people, who shared the common factor of working at different rat-breeding facilities in two different U.S. states and who contracted Seoul virus, most likely contracted the virus from the rats.Special report by Tim Sandle:This is the outcome ...

Ph. Eur. Commission aimed to reduce animal testing

01/25/2017 08:00:20 AM

The recent adoption at its 156th session of the following texts demonstrates the Commission’s commitment to the replacement, reduction and refinement of animal tests in the quality control of medicines.Ph. Eur. General Chapter Adopted: Su ...

Assuring Data Integrity for Life Sciences (book)

01/24/2017 07:00:02 AM

A useful book has been published - 'Assuring Data Integrity for Life Sciences' - edited by Siegfried Schmitt.This new book provides a truly global perspective on data integrity and the solutions available to address this serious issue. It includes ...

Development of cleanrooms: historical review

01/23/2017 07:00:20 AM

Tim Sandle has traced the history ofcleanrooms in two part feature. Part 1 covers the early concept of clean spaces, as required for surgery, and traces these to developments immediately post-war. Part 2 will address the coming of modern cleanroom ...

Microbiology: An oral history

01/22/2017 07:30:02 AM

A BBC radio program about the history of microbiology is available for download as an mp3:Melvyn Bragg and guests discuss the history of microbiology. We have more microbes in our bodies than we have human cells. We fear them as the cause of ...

Scientists examine bacterium found 1,000 feet underground

01/21/2017 07:30:10 AM

Researchers find a bacterium 1,000 feet underground (called Paenibacillus) that is resistant to 18 different antibiotics and uses identical methods of defense as similar species found in soils. The scientists identified five novel pathways that ...

Contamination Control Under Foot

01/20/2017 08:00:05 AM

Control of airborne and surface microorganisms and airborne particles in a cleanroom is achieved through the physical operation of the heating, ventilation, and air conditioning system and cleaning and disinfection techniques.Even with these ...

Antimicrobial Resistance in the Environment

11/22/2016 07:00:01 AM

The class of chemicals characterized as biocides are used in all parts of society from home to hospital, to farms and industry. The presence of biocides selects for genes in microorganisms that can protect against their lethal effects. These ...

The Science Of Christmas

11/21/2016 16:49:16 PM

This book looks at many of the traditions of Christmas and takes an amusing, sideways look st the science behind Christmas. Just how fast will Santa need to travel to deliver gifts to all the children? Where did tinsel come from and is it safe? ...

Mold Monitoring and Control in Pharmaceutical Manufacturing Areas

11/21/2016 07:00:22 AM

Tony Cundell has written an important article on fungi for American Pharmaceutical Review.The introduction reads:“Recent high profile product recalls associated with mold contamination has resulted in more attention from the FDA to fungal ...

Rapid test for Salmonella in chicken developed

11/20/2016 07:30:34 AM

Microbiologists and technologists have joined forces to come up with a rapid and easy-to-use method to detect Salmonella in food such a chicken. The device contributes to contamination control.Despite multiple warning about food storage and ...

Spatiotemporal microbial evolution on antibiotic landscapes

11/19/2016 07:30:06 AM

An interesting research paper, considering a new way to examine the development of antibiotic resistance:A key aspect of bacterial survival is the ability to evolve while migrating across spatially varying environmental challenges. Laboratory ...

New insight into fungal strategy for infecting plants

11/18/2016 07:30:13 AM

Researchers from UPM id reveal how mould from humidity caused by rotting fruits and vegetables unfolds a surprising strategy to infect plants.A team of researchers from Centre for Plant Biotechnology and Genomics (CBGP, UPM-INIA), has published ...

First-generation Cephalosporins show Promise in Tuberculosis Therapy

11/17/2016 07:30:06 AM

Tuberculosis (TB) is the most deadly infectious disease in the world with treatment spanning for up to 6 months; however, in case of MDR-TB, it can even go up to 2 years. Research shows that the cost of developing a new drug is quite huge. Now, ...

New test for detecting prions in urine

11/16/2016 08:00:34 AM

A new test may detect the presence of abnormal proteins indicative of a deadly prion disease known as Creutzfeldt-Jakob Disease (CJD). By adapting an established blood test for variant CJD, researchers at the University College London say the ...

What role will innovation and regulation play in tackling AMR?

11/15/2016 08:00:03 AM

News from the Royal Society of Biology:A panel of expert speakers and delegates from across the life sciences gathered as part of Biology Week to debate how regulation and innovation can help tackle the antimicrobial resistance crisis.Professor ...

Removal of Endotoxin from Protein in Pharmaceutical Processes

11/14/2016 08:00:09 AM

Bacterial endotoxin is the lipopolysaccharide component of the cell wall of Gram-negative bacteria, together with other cellular material that combines to form an endotoxin complex. Endotoxin is pyrogenic and it presents a risk to patients who ...

New FDA Q7 guidance (APIs)

11/13/2016 08:00:21 AM

The U.S. Food and Drug Administration has issued a new guidance document “Q7 Good Manufacturing Practice Guidance for Active Pharmaceutical Ingredients - Guidance for Industry.”This guidance applies to the manufacture of APIs for use in ...

Rifampicin and antibiotic resistance

11/12/2016 05:00:01 AM

A common antibiotic called rifampicin, used to treat tuberculosis, leprosy, and Legionnaire's disease, is becoming less effective as the bacteria that cause the diseases develop more resistance.One of the mechanisms leading to rifampicin's ...

Insight into Pseudomonas aeruginosa survival mechanism

11/11/2016 08:00:20 AM

The bacterium

UN agrees to take action on antimicrobial resistance

11/10/2016 07:30:04 AM

A statement from the Royal Society for Biology, in relation to the United Nations agreeing to take action on antimicrobial resistance“The Learned Society Partnership on Antimicrobial Resistance (LeSPAR) welcomes news of global political and ...

FDA Bans 19 Antibacterial Ingredients from OTC Products

11/09/2016 07:30:21 AM

The FDA is one of the main institutions to increasingly put efforts in reviewing the efficacy and safety of antibacterial products in the market. The final decision of banning these ingredients came after a series of proposals and enquiries ...

The importance of gut microbiota in C. difficile pathogenesis

11/08/2016 07:30:03 AM

Clostridium difficile infection (CDI) is a major cause of healthcare-associated infections worldwide. CDI can cause symptoms from mild diarrhea to life-threatening toxic megacolon. Antibiotics disrupt the normal intestinal microflora enabling ...

How to write a good science article

11/07/2016 17:17:56 PM

Science can easily be misreported, especially for the wilder headline seeking claims. How can a good science article be structured?

Class of drugs effective against Marburg virus and Ebola

11/06/2016 07:30:05 AM

A new drug has shown promise against both Marburg virus and Ebola. This may not be as surprising as it first seems, given the genetic similarities between the two viruses.Filoviruses cause two types of viral haemorrhagic fever: Marburg and Ebola. ...

Research draws a connection between shingles and stroke

11/05/2016 07:30:03 AM

A new study has drawn a connection between the virus that causes the skin rash shingles with an increased chance of suffering from a stroke in later life.The connection has been made by the American Academy of Neurology. Here researchers, from ...

Antibiotic resistance linked with exposure to chlorhexidine

11/04/2016 16:23:03 PM

Klebsiella pneumoniaebacteria exposed to chlorhexidine-containing disinfectants can become resistant to colistin, a last resort antibiotic often used against multidrug resistant pathogens. This is the first study to link exposure to chlorhexidine ...

Counting microscopic sheep? Human and microbial cell mix revealed

11/04/2016 08:30:03 AM

Pick up a text book on microbiology or human physiology. Chances are you’ll stumble across a reference to the number of microorganisms in the human body exceeding the number of cells ten-fold. But is this correct?The microorganisms together ...

New 'layer' of fungi exposed

11/03/2016 09:00:00 AM

In order to optimally utilise fungi, and to fight them when necessary, we require greater insight into the functions that they can perform. Researchers at TU Delft and Utrecht University have exposed a new layer of functional complexity in fungi. ...

Pharmig news # 65

11/03/2016 06:29:09 AM

A new edition of Pharmig news has been issued (edition 65). In this issue there is an article on the revision to the USP chapter (1231) on pharmaceutical water by Tim Sandle. There is also an article on the microbiological quality of non-sterile ...

VERY, VERY SURPRISING USES FOR BOTOX THAT HAVE NOTHING TO DO WITH FOREHEAD WRINKLES

11/02/2016 18:02:00 PM

When most people think of Botox the first thing that usually comes to mind is wrinkle reduction. Indeed, Botox is the world’s most popular treatment for eradicating wrinkles and fine lines.

Drop in tuberculosis rates in the U.K.

11/02/2016 07:00:02 AM

The annual TB report, published today (September 2016), describes the recent epidemiology of TB in England since the launch of the Collaborative TB Strategy in January 2015. It presents new data to the end of 2015 and provides an update on ...

A new class of antibiotics?

11/01/2016 09:00:23 AM

Researchers have made detailed, atomic-level images of a peroxiredoxin, which has revealed a peculiar characteristic of this protein that might form the foundation for an entirely new class of antibiotics.Peroxiredoxin is needed by all cells ...

Risk Assessment and Management for Healthcare Manufacturing

10/31/2016 08:30:16 AM

Tim Sandle has published a new book titled “Risk Assessment and Management for Healthcare Manufacturing: Practical Tips and Case Studies.”Avoidance of hazards and assessment of risk have long been part of the manufacture of pharmaceuticals ...

Shingles And Asthma Linked Together

10/30/2016 08:00:15 AM

A new study has connected shingles to increased rates of acute cardiovascular events such as ischemic stroke. The same research, from the Mayo Clinic, has drawn a connection between developing shingles and asthma.Shingles (caused by the virus ...

Decline In UK Animal Experiments

10/29/2016 07:30:10 AM

Fewer animals were used in experiments in the U.K. during 2014 compared with 2013 (these are the latest statistics, released in January 2016 by the Home Office). The decline is 6 percent, with some 3.8 million procedures undertaken in 2014.The ...

Tracking the evolution of antibiotic resistance

10/28/2016 07:30:27 AM

Researchers have developed a large culturing device to track the evolution of bacteria as they mutate in the presence of antibiotics, revealing that, surprisingly, the fittest mutants were not those most likely to infiltrate higher antibiotic ...