Development of Method of Analysis (MoA), determining of active pharmaceutical ingredient’s assay and dissolution.
| Home | My Account | Directories |
Dissolution of Cyproheptadine HCl Tablet
Published on 2008-11-06 18:53:00
Apparatus : PaddleSpeed : 50 rpmMedium : 900mL ; HCl 0.1 NTime : 30minutesAmount : 1 tablet each testing (Total : 6 tablets)Standard preparation (4 μg/ml)Weight 20.0 mg Cyproheptadine HCl RS, transfer into 50 ml volumetric flask. Dissolve and dilute with ethanol ad volume (ad 50ml). Take (Pipette) 1.0 ml this solution, transfer into 100 ml volumetric flask. Add HCl 0.1 N until volume (ad 100ml).
Assay of Cyproheptadine HCl Tablet
Published on 2008-11-06 18:50:00
Mobile phaseAcetonitrile:isopropyl alcohol: Methanesulfonic acid (3:1000) solution (20:15:65)=20:15:65.While mixing adjust with triethylamine to a pH of 4.0±0.05.Make adjustments if necessary.Stationery phaseL1, μ – Bondapak C 18, 3.9 X 150 MM, 125 A, column 10Standard preparationWeight accurately 40mg of USP Cyproheptadine HCl RS put it into 100ml volumetric flask. Dissolve and add the mobile
