Vinensia - Formulation

Effervescent Tablet Formulation and Manufacture

Published on 2010-08-03 07:13:00

What you should know about effervescent forms before formulate and manufacture it? As per revised definition proposed to US FDA, Effervescent tablet is a tablet intended to be dissolved or dispersed in water before administration. Effervescent tablets are uncoated tablets that generally contain acid substances and carbonates or bicarbonates and which react rapidly in the presence of water by

Polymorphism of Clopidogrel Bisulphate (Form I and Form II)

Published on 2009-02-27 00:25:00

Clopidogrel bisulfate is a platelet aggregation inhibitor, medicine for prophylaxis and the treatment of thrombosis by acting as a platelet aggregation inhibitor. It has now been discovered that clopidogrel hydrogen sulfate can exist in different polymorphic crystalline forms which differ from : stability physical properties spectral characteristics process for their preparation. The

Artesunate and Amodiaquine Tablet Formulation

Published on 2009-01-21 02:27:00

Artesunate and amodiaquine are incompatible, wherein severe degradation of the drugs in presence of each other. The central hypothesis for formulation development was based on the sensitivity of artesunate to the acidity brought by HCl molecules present in the amodiaquine salt that is enhanced by temperature and humidity. Due to the chemical incompatibility of the two drugs which causes mutual