Experts on psychiatry say that men and women who have melancholia and who avoid doing activities due to lack of energy and drive; but psychiatrists have away in helping them through a small package. These medications were sensationalized because they have the power to change the mood of person from gloomy to happy with the sudden burst of energy. Different formulations under various classifications of antidepressants have been developed since their release in the late 1950s. A more recent formulation of these drugs is the selective serotonin reuptake inhibitors (SSRIs) which are marketed with different brand names like Prozac, Paxil and Zoloft, among others. Relief was found in these drugs by some individuals who have had an exacerbation of symptoms of depression and they are now healthy and fit.
 
A turn for the unexpected happened to some of those who were taking SSRIs due to the reported changes that they have felt. An evaluation of the patients medication history is being done by most psychiatrists upon seeing the statistics of antidepressant use. More than a handful of medications have been tried by many users before finding the right drug for them. Many were frustrated and dismayed whenever they had to encounter mysterious side effects of their newly prescribed medication every time they switch medication. A few discoveries made through research have startled many people of the possible effects.
 
Studies concerning the effects of SSRIs in the brain were made because these medications directly affect the brain; thus, they might also influence the memories of its users. A recent research has assessed the conditions of participants regarding their depression and capacity to retain information before being medicated. Data found in the beginning of the study will then be used as basis for the result at the end of the study. Each person may have a unique drug experience because the body reacts differently to each drug. EJ Wadsworth, AP Smith, SA Simpson and SC Moss has published a study about the effects of SSRIs in the cognitive performance of employees, especially on their memory. Further research were asked by the scientific community to dispel any doubts and increase leads in developing better medications. Patients who have been using Zoloft and noticed how their memories changed have filed a Zoloft lawsuit.